Report error Found 8 Enz. Inhib. hit(s) with Target = 'Transthyretin' and Ligand = 'BDBM50108877'
Affinity DataIC50: 3.20E+3nMAssay Description:Stabilization of TTR V3OM mutant (unknown origin) assessed as acid-mediated protein aggregation inhibition ratio incubated for 1 week by absorbance m...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataIC50: 3.00E+4nMAssay Description:Stabilization of wild type TTR (unknown origin) expressed in Escherichia coli assessed as reduction in methanol-induced aggregation incubated for 60 ...More data for this Ligand-Target Pair
Affinity DataKd: 56nMAssay Description:Binding affinity to transthyretin V122I mutant (unknown origin) by ITC methodMore data for this Ligand-Target Pair
Affinity DataKd: 980nMAssay Description:Binding affinity to TTR V3OM mutant (unknown origin) expressed in Escherichia coli incubated for 60 mins by tryptophan intrinsic fluorescence methodMore data for this Ligand-Target Pair
Affinity DataKd: 34nMAssay Description:Binding affinity to wild type TTR (unknown origin) assessed as gibbs free energy change by ITC analysisMore data for this Ligand-Target Pair
Affinity DataKd: 95nMAssay Description:Binding affinity to TTR V30M mutant (unknown origin) by isothermal titration calorimetryMore data for this Ligand-Target Pair
Affinity DataKd: 34nMAssay Description:Binding affinity to wild type TTR (unknown origin) assessed as dissociation constant by ITC assayMore data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding affinity to transthyretin (unknown origin) by ITC methodMore data for this Ligand-Target Pair
