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Report error Found 4 Enz. Inhib. hit(s) with Target = 'Transthyretin' and Ligand = 'BDBM50197881'
TargetTransthyretin(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197881(CHEMBL3890392)
Affinity DataIC50:  2.49E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197881(CHEMBL3890392)
Affinity DataIC50:  2.51E+3nMAssay Description:Stabilization of recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as inhibition of amyloid beta formation by measuri...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197881(CHEMBL3890392)
Affinity DataKd:  3.90nMAssay Description:Binding affinity to recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as dissociation constants for first binding sit...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransthyretin(Human)
Universidade De Coimbra

Curated by ChEMBL
LigandPNGBDBM50197881(CHEMBL3890392)
Affinity DataKd:  278nMAssay Description:Binding affinity to recombinant human wild type TTR expressed in Escherichia coli BL21 (DE3) assessed as dissociation constants for second binding si...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed