Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1' and Ligand = 'BDBM522000'
TargetTyrosine-protein kinase JAK1(Homo sapiens (Human))
Genentech, Inc.

US Patent
LigandPNGBDBM522000(N-[3-[6-(difluoromethoxy)-3- oxo-4H-1,4-benzothiaz...)
Show SMILES Cn1cc(NC(=O)c2cnn3cccnc23)c(n1)-c1cc2SCC(=O)Nc2cc1OC(F)F
Show InChI InChI=1S/C20H15F2N7O3S/c1-28-8-13(26-19(31)11-7-24-29-4-2-3-23-18(11)29)17(27-28)10-5-15-12(25-16(30)9-33-15)6-14(10)32-20(21)22/h2-8,20H,9H2,1H3,(H,25,30)(H,26,31)
Affinity DataKi:  0.0700nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid