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Found 3 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1 [850-1154]' and Ligand = 'BDBM103727'
TargetTyrosine-protein kinase JAK1 [850-1154]()
Galapagos

US Patent
LigandPNGBDBM103727(US10112907, Example 00033 | US10206907, Compound 2...)
Affinity DataIC50:  47.1nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103727(US10112907, Example 00033 | US10206907, Compound 2...)
Affinity DataIC50:  50nMAssay Description:JAK1 (IC50): Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) is purchased from Carna Biosciences. 10 ng of JAK1...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK1 [850-1154](Homo sapiens (Human))
Galapagos

US Patent
LigandPNGBDBM103727(US10112907, Example 00033 | US10206907, Compound 2...)
Affinity DataIC50: <100nMAssay Description:Recombinant human JAK1 catalytic domain (amino acids 850-1154; catalog number 08-144) was purchased from Carna Biosciences. 10 ng of JAK1 was incubat...More data for this Ligand-Target Pair
In DepthDetails US Patent