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Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50069321'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50069321(CHEMBL3403546 | US9688661, 1-(5-Chloro-2-ethylphen...)
Affinity DataIC50:  20nMAssay Description:Assays were performed with the commercially available JAK2 kinase domain (Invitrogen, Eugene, Oreg.) that showed a linear kinetic without prephosphor...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Nerviano Medical Sciences

US Patent
LigandPNGBDBM50069321(CHEMBL3403546 | US9688661, 1-(5-Chloro-2-ethylphen...)
Affinity DataIC50:  20nMAssay Description:Inhibition of recombinant epitope-tagged JAK2 (808 to 1132) (unknown origin) using LPLDKDYYVVREPGQ as substrate by beta-countiing analysis in presenc...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed