Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM50303074'
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50303074((R)-3-(6-(1-(4-fluorophenyl)propylamino)pyrimidin-...)
Affinity DataIC50: 0.600nMAssay Description:Inhibition of JAK2 by radiometric assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50303074((R)-3-(6-(1-(4-fluorophenyl)propylamino)pyrimidin-...)
Affinity DataIC50: 270nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in GMCSF-stimulated human TF1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed