Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM521921'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech, Inc.

US Patent
LigandPNGBDBM521921(N-[3-[6-(difluoromethoxy)- 3,4-dihydro-2H-1,4- ben...)
Show SMILES FC(F)Oc1cc2NCCOc2cc1-c1n[nH]cc1NC(=O)c1cnn2cccnc12
Show InChI InChI=1S/C19H15F2N7O3/c20-19(21)31-14-7-12-15(30-5-3-22-12)6-10(14)16-13(9-24-27-16)26-18(29)11-8-25-28-4-1-2-23-17(11)28/h1-2,4,6-9,19,22H,3,5H2,(H,24,27)(H,26,29)
Affinity DataKi:  0.0800nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid