Compile Data Set for Download or QSAR
Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK2' and Ligand = 'BDBM521935'
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Genentech, Inc.

US Patent
LigandPNGBDBM521935(N-[3-[5-(difluoromethoxy)-2- methyl-benzothiophen-...)
Show SMILES Cc1cc2cc(OC(F)F)c(cc2s1)-c1n[nH]cc1NC(=O)c1cnn2cccnc12
Show InChI InChI=1S/C20H14F2N6O2S/c1-10-5-11-6-15(30-20(21)22)12(7-16(11)31-10)17-14(9-24-27-17)26-19(29)13-8-25-28-4-2-3-23-18(13)28/h2-9,20H,1H3,(H,24,27)(H,26,29)
Affinity DataKi:  0.0600nMAssay Description:The activity of the isolated recombinant JAK1 and JAK2 kinase domain was measured by monitoring phosphorylation of a peptide derived from JAK3 (Val-A...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid