Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK3' and Ligand = 'BDBM50303070'
TargetTyrosine-protein kinase JAK3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50303070((R)-3-(6-(1-(4-fluorophenyl)ethylamino)pyrimidin-4...)
Affinity DataIC50: 7nMAssay Description:Inhibition of JAK3 by radiometric assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed
TargetTyrosine-protein kinase JAK3(Human)
Vertex Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50303070((R)-3-(6-(1-(4-fluorophenyl)ethylamino)pyrimidin-4...)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of JAK2-mediated STAT5 phosphorylation in GMCSF-stimulated human HT2 cellsMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/27/2012
Entry Details Article
PubMed