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Found 1 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase SYK' and Ligand = 'BDBM290763'
TargetTyrosine-protein kinase SYK(Homo sapiens (Human))
Portola Pharmaceuticals

US Patent
LigandPNGBDBM290763(2-((1R,2S)-2- aminocyclohexylamino)- 4-(1-methyl-1...)
Affinity DataIC50:  5.5nMpH: 7.5 T: 2°CAssay Description:Potency of candidate molecules for inhibiting syk tyrosine phosphorylation activity is assessed by measuring the ability of a test compound to inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent