Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11 [E76Z]' and Ligand = 'BDBM497077'
LigandChemical structure of BindingDB Monomer ID 497077BDBM497077(US11001561, Compound 66a | US11702392, Compound 66...)
Affinity DataIC50: 97nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 497077BDBM497077(US11001561, Compound 66a | US11702392, Compound 66...)
Affinity DataIC50: 200nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent