Compile Data Set for Download or QSAR
Report error Found 2 Enz. Inhib. hit(s) with Target = 'Tyrosine-protein phosphatase non-receptor type 11 [E76Z]' and Ligand = 'BDBM608845'
LigandChemical structure of BindingDB Monomer ID 608845BDBM608845(US11702392, Compound 23b | (3M)-6-[(3S,4S)-4-amino...)
Affinity DataIC50: 21nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent

LigandChemical structure of BindingDB Monomer ID 608845BDBM608845(US11702392, Compound 23b | (3M)-6-[(3S,4S)-4-amino...)
Affinity DataIC50: 1.20E+4nMAssay Description:The inhibition of SHP2 by compounds of the invention was monitored using the surrogate substrate DiFMUP after protein activation by a peptide bearing...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/18/2023
Entry Details
US Patent