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Found 5 Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase 30' and Ligand = 'BDBM404571'
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404571((R)-N-(1-cyanopyrrolidin-3-yl)-3-fluoro-4-(4-methy...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404571((R)-N-(1-cyanopyrrolidin-3-yl)-3-fluoro-4-(4-methy...)
Affinity DataIC50: <100nMAssay Description:USP30 Biochemical Fluorescence Intensity Kinetic Assay.Reactions were performed in duplicate in black 384 well plates (small volume, Greiner 784076) ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404571((R)-N-(1-cyanopyrrolidin-3-yl)-3-fluoro-4-(4-methy...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404571((R)-N-(1-cyanopyrrolidin-3-yl)-3-fluoro-4-(4-methy...)
Affinity DataIC50: <100nMAssay Description:USP30 biochemical fluorescence intensity IC50 assay Dilution plates were prepared at 21 times the final concentration (2100 μM for a final conce...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetUbiquitin carboxyl-terminal hydrolase 30(Homo sapiens (Human))
Missions Therapeutics

US Patent
LigandPNGBDBM404571((R)-N-(1-cyanopyrrolidin-3-yl)-3-fluoro-4-(4-methy...)
Affinity DataIC50: <100nMAssay Description:Dilution plates were prepared at 21 times the final concentration (2100 μM for a final concentration of 100 μM) in 50% DMSO in a 96-well po...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent