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Report error Found 7 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 1' and Ligand = 'BDBM24773'
TargetVascular endothelial growth factor receptor 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24773BDBM24773(N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2022
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24773BDBM24773(N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyr...)
Affinity DataIC50: 2nMpH: 7.5 T: 2°CAssay Description:In vitro kinase assays were done to establish IC50 values against recombinant enzymes using homogeneous time-resolved fluorescence (HTRF) assay. For ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/13/2008
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24773BDBM24773(N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR1 (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/14/2017
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24773BDBM24773(N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyr...)
Affinity DataIC50: 2nMAssay Description:Inhibition of VEGFR1More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/17/2013
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24773BDBM24773(N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyr...)
Affinity DataKd:  12nMAssay Description:Binding constant for FLT1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
12/25/2012
Entry Details Article
PubMed
TargetVascular endothelial growth factor receptor 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24773BDBM24773(N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyr...)
Affinity DataKd:  12nMpH: 7.4 T: 2°CAssay Description:Kinase inhibitors are a new class of therapeutics with a propensity to inhibit multiple targets. The biological consequences of multi-kinase activity...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/14/2009
Entry Details
PCBioAssay
TargetVascular endothelial growth factor receptor 1(Human)
West China Hospital of Sichuan University

Curated by ChEMBL
LigandChemical structure of BindingDB Monomer ID 24773BDBM24773(N-(3,3-dimethyl-2,3-dihydro-1H-indol-6-yl)-2-[(pyr...)
Affinity DataKd:  12nMAssay Description:Binding constant for FLT1 kinase domainMore data for this Ligand-Target Pair
In Depth
Date in BDB:
7/19/2012
Entry Details Article
PubMed