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Found 3 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM5815'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM5815(3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50:  3nMAssay Description:The assay was using baculovirus-expressed recombinant protein kinase purified as the intracellular domain fused by GST tag, interacting with biotinyl...More data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM5815(3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50:  3.02nMAssay Description:Inhibition of KDRMore data for this Ligand-Target Pair
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Glaxosmithkline

LigandPNGBDBM5815(3-{4-[4-amino-6-(4-methoxyphenyl)furo[2,3-d]pyrimi...)
Affinity DataIC50:  15.5nMpH: 7.5 T: 2°CAssay Description:The assay uses purified GST-Tie-2 or GST-6x His-VEGFR2 interacting with biotinylated peptide substrates. HTRF is based on the proximity of europium c...More data for this Ligand-Target Pair