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Found 4 Enz. Inhib. hit(s) with Target = 'Vascular endothelial growth factor receptor 2' and Ligand = 'BDBM6190'
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM6190(3-tert-butyl-1-(2-{[4-(diethylamino)butyl]amino}-6...)
Affinity DataIC50:  100nMAssay Description:Inhibition of VEGFR2 (unknown origin) overexpressed in mouse NIH/ 3T3 cells incubated for 5 mins followed by stimulation with VEGF for 5 mins by immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM6190(3-tert-butyl-1-(2-{[4-(diethylamino)butyl]amino}-6...)
Affinity DataIC50:  100nMAssay Description:Inhibition of VEGFR2 (unknown origin) overexpressed in mouse NIH/ 3T3 cells incubated for 5 mins followed by stimulation with VEGF for 5 mins by immu...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM6190(3-tert-butyl-1-(2-{[4-(diethylamino)butyl]amino}-6...)
Affinity DataIC50:  120nMAssay Description:Tha assay was using human VEGFR-2 in DELFIA (dissociation-enhanced lanthanide fluoroimmunoassay) format. IC50 is the concentration of inhibitor that ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVascular endothelial growth factor receptor 2(Homo sapiens (Human))
Shanghai Institute Of Materia Medica

Curated by ChEMBL
LigandPNGBDBM6190(3-tert-butyl-1-(2-{[4-(diethylamino)butyl]amino}-6...)
Affinity DataEC50:  250nMAssay Description:Inhibition of VEGFR2 by cellular assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed