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Compile Data Set for Download or QSAR
Found
1
Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM14399'
Target
cGMP-specific 3',5'-cyclic phosphodiesterase
(Homo sapiens (Human))
Pfizer Inc
Ligand
BDBM14399
(2-(azetidin-3-yl)-5-(5-acetyl-2-propoxypyridin-3-y...)
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Affinity Data
IC50: 34nM
pH: 7.4 T: 2°C
Assay Description:
PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...
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