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Found 1 Enz. Inhib. hit(s) with Target = 'cGMP-specific 3',5'-cyclic phosphodiesterase' and Ligand = 'BDBM14409'
TargetcGMP-specific 3',5'-cyclic phosphodiesterase(Homo sapiens (Human))
Pfizer

LigandPNGBDBM14409(2-(azetidin-3-yl)-5-(2-butoxy-5-acetylpyridin-3-yl...)
Affinity DataIC50:  21nMAssay Description:PDE5 or PDE6 catalytic activity was monitored by measuring the hydrolysis of [3H]-cGMP to [3H]-GMP using a scintillation proximity assay (SPA). [3H]-...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed