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TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465535(CHEMBL4278314)
Affinity DataKd:  560nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465536(CHEMBL4282793)
Affinity DataKd:  890nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465537(CHEMBL4286225)
Affinity DataKd:  590nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465538(CHEMBL4284197)
Affinity DataKd:  940nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465544(CHEMBL4285802)
Affinity DataKd:  360nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465545(CHEMBL4293000)
Affinity DataKd:  860nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465540(CHEMBL4282396)
Affinity DataKd:  310nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465533(CHEMBL4289190)
Affinity DataKd:  770nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465539(CHEMBL4292433)
Affinity DataKd:  320nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465543(CHEMBL4278778)
Affinity DataKd:  190nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465546(CHEMBL4277865)
Affinity DataKd:  540nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetBromodomain-containing protein 4(Human)
Aix-Marseille University

Curated by ChEMBL
LigandPNGBDBM50465541(CHEMBL4284735)
Affinity DataKd:  410nMAssay Description:Binding affinity to TEV cleavage site-fused-His-tagged BRD4(BD1) (unknown origin) by isothermal-titration calorimetryMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506315(CHEMBL4579923)
Affinity DataKd:  501nMAssay Description:Binding affinity to PI3Kgamma in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506315(CHEMBL4579923)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to PI3Kdelta in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506315(CHEMBL4579923)
Affinity DataKd:  158nMAssay Description:Binding affinity to PI3Kalpha in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506323(CHEMBL4556087)
Affinity DataKd:  50nMAssay Description:Binding affinity to PI3Kbeta in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506323(CHEMBL4556087)
Affinity DataKd:  2.51E+3nMAssay Description:Binding affinity to PI3Kgamma in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506315(CHEMBL4579923)
Affinity DataKd:  158nMAssay Description:Binding affinity to PI3Kbeta in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506315(CHEMBL4579923)
Affinity DataKd:  63nMAssay Description:Binding affinity to VPS34 in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506323(CHEMBL4556087)
Affinity DataKd:  2nMAssay Description:Binding affinity to VPS34 in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506323(CHEMBL4556087)
Affinity DataKd:  316nMAssay Description:Binding affinity to PI3Kalpha in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50506323(CHEMBL4556087)
Affinity DataKd:  0.251nMAssay Description:Binding affinity to PI3Kdelta in human HL60 cell extract measured after 2 hrs by kinobeads based pull down assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  1.88E+4nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50511078(CHEBI:75934 | AS-1404 | ASA-404 | ASA404 | DMXAA |...)
Affinity DataEC50:  3.52E+4nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558664(CHEMBL4752156)
Affinity DataEC50:  2.20E+3nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558665(CHEMBL4776666)
Affinity DataEC50:  8.40E+3nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558666(CHEMBL4797172)
Affinity DataEC50:  1.59E+4nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50509411(CHEMBL4552089)
Affinity DataEC50:  6.10E+3nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558667(CHEMBL4761077)
Affinity DataEC50:  1.74E+4nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558668(CHEMBL4762242)
Affinity DataEC50:  4.00E+3nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558669(CHEMBL4783642)
Affinity DataEC50:  1.16E+4nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558670(CHEMBL4797965)
Affinity DataEC50:  5.10E+3nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558671(CHEMBL4751982)
Affinity DataEC50:  600nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558672(CHEMBL4753213)
Affinity DataEC50:  9.10E+3nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Mouse)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558673(CHEMBL4800420)
Affinity DataEC50:  5.00E+3nMAssay Description:Activation of STING in mouse RAW-Lucia ISG cells assessed as induction of type I IFNs stimulation by measuring induction of IRF pathway incubated for...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50506263(CHEMBL4465054 | US11401295, Compound 2',3'-cGAMP)
Affinity DataEC50:  7.20E+3nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558664(CHEMBL4752156)
Affinity DataEC50:  1.90E+3nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558673(CHEMBL4800420)
Affinity DataEC50:  2.30E+3nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558672(CHEMBL4753213)
Affinity DataEC50:  1.40E+3nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558671(CHEMBL4751982)
Affinity DataEC50:  300nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558670(CHEMBL4797965)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558669(CHEMBL4783642)
Affinity DataEC50:  1.00E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558668(CHEMBL4762242)
Affinity DataEC50:  1.60E+3nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558667(CHEMBL4761077)
Affinity DataEC50:  1.79E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50509411(CHEMBL4552089)
Affinity DataEC50:  1.25E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558666(CHEMBL4797172)
Affinity DataEC50:  1.51E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558665(CHEMBL4776666)
Affinity DataEC50:  5.10E+3nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of IRF pathway incubated for 48 hrs by lu...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558665(CHEMBL4776666)
Affinity DataEC50:  1.59E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of NF-kappaB pathway incubated for 48 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50558666(CHEMBL4797172)
Affinity DataEC50:  6.06E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of NF-kappaB pathway incubated for 48 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetStimulator of interferon genes protein(Human)
Invivogen

Curated by ChEMBL
LigandPNGBDBM50509411(CHEMBL4552089)
Affinity DataEC50:  5.43E+4nMAssay Description:Activation of STING in human THP-1-Dual cells assessed as induction of type I IFNs by measuring stimulation of NF-kappaB pathway incubated for 48 hrs...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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