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TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403254(CHEMBL51389)
Affinity DataIC50:  0.600nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403250(CHEMBL51780)
Affinity DataIC50:  1nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403253(CHEMBL301751)
Affinity DataIC50:  1.20nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085454(CHEMBL90388 | N-formyl hydroxylamine containing di...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282859((2S,4S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-pr...)
Affinity DataIC50:  1.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403257(CHEMBL51438)
Affinity DataIC50:  1.70nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085460((4S,7S,12bR)-7-[(R)-2-Benzyl-3-(formyl-hydroxy-ami...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282855((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  2nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403261(CHEMBL51498)
Affinity DataIC50:  2.10nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403251(CHEMBL299441)
Affinity DataIC50:  2.20nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282848(1-{2-[(S)-3-(2-Chloro-phenyl)-2-mercaptomethyl-pro...)
Affinity DataIC50:  2.20nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403258(CHEMBL301364)
Affinity DataIC50:  2.40nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282845((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  2.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085459((S)-3-Biphenyl-4-yl-2-[(S)-3-methyl-2-(phosphonome...)
Affinity DataIC50:  3nMAssay Description:Inhibition of Neutral endopeptidaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403280(CHEMBL65545)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403252(CHEMBL54036)
Affinity DataIC50:  3.10nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085460((4S,7S,12bR)-7-[(R)-2-Benzyl-3-(formyl-hydroxy-ami...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282851((S)-2-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  3.90nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282861((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  4nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282861((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  4nMAssay Description:Tested in vitro for inhibition of Angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403254(CHEMBL51389)
Affinity DataIC50:  4.40nMAssay Description:Tested in vitro for inhibition of Angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403261(CHEMBL51498)
Affinity DataIC50:  4.80nMAssay Description:Tested in vitro for inhibition of Angiotensin converting enzyme (ACE)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048505((S)-2-[(3S,7S)-3-((S)-2-Mercapto-3-phenyl-propiony...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048509((3S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073120((4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataIC50:  5nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE) isolated from rabbit lung extract using hippuryl-L-histidyl-L-leucine (HHL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403255(CHEMBL50559)
Affinity DataIC50:  5.20nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085454(CHEMBL90388 | N-formyl hydroxylamine containing di...)
Affinity DataIC50:  5.30nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403268(CHEMBL299875)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085457(CHEMBL89533 | {(S)-6-[(R)-2-Benzyl-3-(formyl-hydro...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50024101((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50:  5.70nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073120((4S,6S,9aS)-6-((S)-2-Mercapto-3-phenyl-propionylam...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403277(CHEMBL61566)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against angiotensin converting enzyme (ACE) in rat was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50048512(CHEMBL299639 | [(S)-3-((S)-2-Mercapto-3-phenyl-pro...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against neutral endopeptidase (NEP) was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048512(CHEMBL299639 | [(S)-3-((S)-2-Mercapto-3-phenyl-pro...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibition of purified rat kidney Neutral endopeptidase.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50073118(CHEMBL319237 | [(S)-8-((S)-2-Mercapto-3-phenyl-pro...)
Affinity DataIC50:  6nMAssay Description:In vitro inhibitory activity against Angiotensin I converting enzyme (ACE) isolated from rabbit lung extract using hippuryl-L-histidyl-L-leucine (HHL...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50048512(CHEMBL299639 | [(S)-3-((S)-2-Mercapto-3-phenyl-pro...)
Affinity DataIC50:  6nMAssay Description:Inhibition of Neutral Endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50048512(CHEMBL299639 | [(S)-3-((S)-2-Mercapto-3-phenyl-pro...)
Affinity DataIC50:  6.10nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282852(1-[2-((S)-2-Mercaptomethyl-3-o-tolyl-propionylamin...)
Affinity DataIC50:  6.20nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403266(CHEMBL415932)
Affinity DataIC50:  6.30nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282862((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataIC50:  6.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50282861((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  6.60nMAssay Description:Tested in vitro for inhibition of neutral endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282847((2S,4S)-4-Cyclohexyl-1-[(S)-2-((S)-2-mercaptomethy...)
Affinity DataIC50:  6.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Rattus norvegicus (Rat))
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282861((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  6.60nMAssay Description:In vitro inhibition of rat kidney neutral endopeptidase (NEP) by fluorometric assay using Dansyl-Gly-Phe-Arg as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetNeprilysin(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403266(CHEMBL415932)
Affinity DataIC50:  7nMAssay Description:Inhibition of Neutral Endopeptidase (NEP)More data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403274(CHEMBL66481)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory activity against angiotensin converting enzyme (ACE) in rat was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50085452((S)-2-[((S)-6-Amino-2-methanesulfonylamino-hexanoy...)
Affinity DataIC50:  7nMAssay Description:Inhibition of Angiotensin I converting enzymeMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048504(CHEMBL148155 | [(3S,7R)-7-Allyl-3-((S)-2-mercapto-...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50282845((S)-1-[(S)-2-((S)-2-Mercaptomethyl-3-phenyl-propio...)
Affinity DataIC50:  7.80nMAssay Description:In vitro inhibition of rabbit lung Angiotensin I converting enzyme (ACE) using Hippuryl-His-Leu as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Homo sapiens (Human))
TBA

Curated by ChEMBL
LigandPNGBDBM50403280(CHEMBL65545)
Affinity DataIC50:  8nMAssay Description:In vitro inhibitory activity against angiotensin converting enzyme (ACE) in rat was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetAngiotensin-converting enzyme(Oryctolagus cuniculus)
Bristol-Myers Squibb Pharmaceutical Research Institute

Curated by ChEMBL
LigandPNGBDBM50048506(CHEMBL104054 | [(3S,7S)-3-((S)-2-Mercapto-3-phenyl...)
Affinity DataIC50:  8nMAssay Description:In vitro inhibition of Angiotensin I converting enzyme isolated from rabbit lung extract.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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