Report error Found 1143 with Last Name = 'aubé' and Initial = 'j'
Affinity DataKi: 0.590nM ΔG°: -52.7kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataKi: 0.900nMAssay Description:Displacement of [3H]-N-methylspiperone from D3 receptor (unknown origin) measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
3D Structure (crystal)TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataKi: 0.940nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer by topcount assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 2.20nM ΔG°: -49.4kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 2.5nM ΔG°: -49.1kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 3.30nM ΔG°: -48.4kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 3.5nM ΔG°: -48.3kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 3.90nM ΔG°: -48.0kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 4nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 4nM ΔG°: -47.9kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 4.40nM ΔG°: -47.7kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
TargetD(2) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataKi: 4.70nMAssay Description:Displacement of [3H]-methylspiperon from human D2RL expressed in HEK293 cell membranes measured after 90 mins by topcount assayMore data for this Ligand-Target Pair
Affinity DataKi: 4.80nM ΔG°: -47.5kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 5nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 5.40nM ΔG°: -47.2kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataKi: 5.60nMAssay Description:Displacement of [3H]-7-OH-DPAT from human D3R expressed in HEK293 cell membranes measured after 90 mins in Tris buffer containing NaCl by topcount as...More data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 6.20nM ΔG°: -46.8kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 6.60nM ΔG°: -46.7kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 7nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 7.10nM ΔG°: -46.5kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 7.20nM ΔG°: -46.5kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 7.20nM ΔG°: -46.5kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 7.60nM ΔG°: -46.3kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 7.80nM ΔG°: -46.3kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 8nM ΔG°: -46.2kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
TargetD(3) dopamine receptor(Human)
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
National Institute of Neurological Disorders and Stroke
Curated by ChEMBL
Affinity DataKi: 8.20nMAssay Description:Displacement of [3H]-methylspiperon from human D3R expressed in HEK293 cell membranes measured after 90 mins in EBSS buffer by topcount assayMore data for this Ligand-Target Pair
Affinity DataKi: 8.30nM ΔG°: -46.1kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 8.30nM ΔG°: -46.1kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 9nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 9.30nM ΔG°: -45.8kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 10nM ΔG°: -45.7kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 10nM ΔG°: -45.7kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 10nMAssay Description:Displacement of [3H]pentazocine from guinea pig sigma1 receptor measured after 90 mins by microbeta scintillation counting methodMore data for this Ligand-Target Pair
Affinity DataKi: 10nM ΔG°: -45.7kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -45.4kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
Affinity DataKi: 11nM ΔG°: -45.4kJ/molepH: 7.4 T: 25°CAssay Description:Radioligand binding assays were performed as previously detailed [Yan et al., Biochemistry, 48:6898-6908]. In brief, crude cell membranes were prepar...More data for this Ligand-Target Pair
