Compile Data Set for Download or QSAR
Report error Found 6555 with Last Name = 'bömer' and Initial = 'u'
TargetCyclin-dependent kinase 9(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM180837(US9133171, 42)
Affinity DatapH: 8.0 T: 2°CAssay Description:Recombinant full-length His-tagged human CDK9 and CycT1, expressed in insect cells and purified by Ni-NTA affinity chromatography, were purchase from...More data for this Ligand-Target Pair
In Depth
Date in BDB:
5/23/2016
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679127(US11998539, Example 569 | US11998539, Example 570 ...)
Affinity DataIC50: 0.0700nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555110(US11339157, Example 4 | 3-[(3-fluorophenyl)amino]-...)
Affinity DataIC50: 0.0720nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555112(US11339157, Example 6 | 3-[(3-fluorophenyl)amino]-...)
Affinity DataIC50: 0.0720nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555115(US11339157, Example 9 | 3-[(3,5-difluorophenyl)ami...)
Affinity DataIC50: 0.0720nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555116(US11339157, Example 10 | 3-[(3,5-difluorophenyl)am...)
Affinity DataIC50: 0.0720nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555118(US11339157, Example 12 | 3-[(2-bromo-3-fluoropheny...)
Affinity DataIC50: 0.0860nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555136(US11339157, Example 30 | 3-[(3,5-difluoro-2-methox...)
Affinity DataIC50: 0.0970nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555137(US11339157, Example 31 | 3-[(3,5-difluoro-2-methox...)
Affinity DataIC50: 0.0990nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM302404(US9598416, Example 50)
Affinity DataIC50: 0.100nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678990(US11998539, Example 432 | (rac)-1-methyl-4-[4-meth...)
Affinity DataIC50: 0.100nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679127(US11998539, Example 569 | US11998539, Example 570 ...)
Affinity DataIC50: 0.100nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679109(US11998539, Example 551 | 7-[(2-hydroxyethyl)(meth...)
Affinity DataIC50: 0.100nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555123(US11339157, Example 17 | 3-[(3-fluoro-2-methoxyphe...)
Affinity DataIC50: 0.113nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555124(US11339157, Example 18 | 3-{[2-(difluoromethoxy)-3...)
Affinity DataIC50: 0.120nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555110(US11339157, Example 4 | 3-[(3-fluorophenyl)amino]-...)
Affinity DataIC50: 0.131nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555122(US11339157, Example 16 | 3-[(3-fluoro-2-methoxyphe...)
Affinity DataIC50: 0.138nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555127(US11339157, Example 21 | 3-[(3-fluoro-2-methylphen...)
Affinity DataIC50: 0.138nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555126(US11339157, Example 20 | 3-[(3-fluoro-2-methylphen...)
Affinity DataIC50: 0.149nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555125(US11339157, Example 19 | 3-{[2-(difluoromethoxy)-3...)
Affinity DataIC50: 0.155nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555137(US11339157, Example 31 | 3-[(3,5-difluoro-2-methox...)
Affinity DataIC50: 0.161nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555128(US11339157, Example 22 | 3-{[2-(2,2-difluoroethyl)...)
Affinity DataIC50: 0.176nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555123(US11339157, Example 17 | 3-[(3-fluoro-2-methoxyphe...)
Affinity DataIC50: 0.177nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM302362(6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-...)
Affinity DataIC50: 0.200nMAssay Description:Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM302362(6-[(2-Aminoethoxy)methyl]-5-(7-methoxy-5-methyl-1-...)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM302363(N-{[4-Amino-5-(7-methoxy-5-methyl-1-benzothiophen-...)
Affinity DataIC50: 0.200nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM194899(US9206184, 80)
Affinity DataIC50: 0.200nMpH: 7.0 T: 2°CAssay Description:For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/3/2016
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679071(US11998539, Example 513 | (rac)-6-bromo-1- methyl-...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679108(US11998539, Example 550 | 7-[(2-hydroxyethyl)amino...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679095(US11998539, Example 537 | (−)-6-bromo-1-meth...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679096(US11998539, Example 538 | US11998539, Example 539 ...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM679102(US11998539, Example 544 | (rac)-1,6-dimethyl-4-[4-...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetDiacylglycerol kinase alpha(Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM678983(US11998539, Example 425 | (rac)-1-methyl-4-[4-(5-m...)
Affinity DataIC50: 0.200nMAssay Description:For the assay 50 nl of a 100-fold concentrated solution of the test compound in dimethyl sulfoxide (DMSO, Sigma) was pipetted into either a white 153...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/9/2024
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555136(US11339157, Example 30 | 3-[(3,5-difluoro-2-methox...)
Affinity DataIC50: 0.209nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555112(US11339157, Example 6 | 3-[(3-fluorophenyl)amino]-...)
Affinity DataIC50: 0.212nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555122(US11339157, Example 16 | 3-[(3-fluoro-2-methoxyphe...)
Affinity DataIC50: 0.212nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555127(US11339157, Example 21 | 3-[(3-fluoro-2-methylphen...)
Affinity DataIC50: 0.213nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555118(US11339157, Example 12 | 3-[(2-bromo-3-fluoropheny...)
Affinity DataIC50: 0.218nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555117(US11339157, Example 11 | 3-{[2-(difluoromethoxy)ph...)
Affinity DataIC50: 0.220nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555125(US11339157, Example 19 | 3-{[2-(difluoromethoxy)-3...)
Affinity DataIC50: 0.239nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227802(US10047096, 65 | rac-4-[(2-Fluoro-5-hydroxy-4-meth...)
Affinity DataIC50: 0.246nMpH: 7.0Assay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555135(US11339157, Example 29 | 3-[(3,4-difluoro-2-methox...)
Affinity DataIC50: 0.246nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555129(US11339157, Example 23 | 3-{[2-(2,2-difluoroethyl)...)
Affinity DataIC50: 0.259nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555132(US11339157, Example 26 | 3-[(2-ethoxy-3-fluorophen...)
Affinity DataIC50: 0.268nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227931(US10047096, 192 | trans-Ethyl 3-[({4-[(2-fluoro-5-...)
Affinity DataIC50: 0.274nMpH: 7.0Assay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555103(US11339157, Example 3 | 2-[3-(benzyloxy)pyridin-4-...)
Affinity DataIC50: 0.280nMAssay Description:Exon 20-Mutant-EGFR(D770_N771insSVD): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
Entry Details
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TargetVascular endothelial growth factor receptor 2(Human)
Bayer Pharma Aktiengesellschaft

US Patent
LigandPNGBDBM227801(US10047096, 64 | 4-[(2-Fluoro-5-hydroxy-4-methylph...)
Affinity DataIC50: 0.287nMpH: 7.0Assay Description:The kinase used was a recombinant fusion protein composed of N-terminal GST and a C-terminal fragment of human KDR (amino acids D807-V1356), expresse...More data for this Ligand-Target Pair
In Depth
Date in BDB:
10/2/2018
Entry Details
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TargetFibroblast growth factor receptor 1(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM302404(US9598416, Example 50)
Affinity DataIC50: 0.300nMAssay Description:Usually, test compounds were tested on the same microtiter plate at 11 different concentrations in the range of 20 μM to 0.1 nM (e.g. 20 μM...More data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetFibroblast growth factor receptor 3(Human)
Bayer Intellectual Property

US Patent
LigandPNGBDBM302385(4-{[4-Amino-5-(5-chloro-7-methoxy-1-benzothiophen-...)
Affinity DataIC50: 0.300nMMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/29/2019
Entry Details
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TargetEpidermal growth factor receptor [669-770,'SVD',771-1210](Human)
Bayer Aktiengesellschaft

US Patent
LigandPNGBDBM555124(US11339157, Example 18 | 3-{[2-(difluoromethoxy)-3...)
Affinity DataIC50: 0.300nMAssay Description:Exon 20-Mutant-EGFR(V769_D770insASV): For the assay 50 nl of a 100-fold concentrated solution of the test compound in DMSO was pipetted into either a...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/29/2022
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