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Report error Found 10 with Last Name = 'barnes' and Initial = 'mj'
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Paradigm Therapeutics

Curated by ChEMBL
LigandPNGBDBM50476508(CHEMBL234487)
Affinity DataIC50:  3nMAssay Description:Inhibition of MAPK p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Paradigm Therapeutics

Curated by ChEMBL
LigandPNGBDBM50476509(CHEMBL234486)
Affinity DataIC50:  7nMAssay Description:Inhibition of MAPK p38More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetMitogen-activated protein kinase 11/12/13/14(Homo sapiens (Human))
Paradigm Therapeutics

Curated by ChEMBL
LigandPNGBDBM13533(1-[2-(4-methylphenyl)-5-tert-butyl-pyrazol-3-yl]-3...)
Affinity DataIC50:  9nMAssay Description:Inhibition of MAPK p38More data for this Ligand-Target Pair
TargetSodium-dependent noradrenaline transporter(Homo sapiens (Human))
Paradigm Therapeutics

Curated by ChEMBL
LigandPNGBDBM50183656((R)-1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)...)
Affinity DataIC50:  200nMAssay Description:Inhibition of noradrenaline reuptake at human recombinant noradrenaline transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219334(CHEMBL267102)
Affinity DataIC50:  1.31E+3nMAssay Description:Inhibition of human Phosphodiesterase 7 of HUT-78 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219333(CHEMBL11073)
Affinity DataIC50:  2.31E+3nMAssay Description:Inhibition of human Phosphodiesterase 7 of HUT-78 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Homo sapiens (Human))
Paradigm Therapeutics

Curated by ChEMBL
LigandPNGBDBM50183656((R)-1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)...)
Affinity DataIC50:  4.20E+3nMAssay Description:Inhibition of serotonin reuptake at human recombinant serotonin transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219336(CHEMBL11499)
Affinity DataIC50:  4.22E+3nMAssay Description:Inhibition of human Phosphodiesterase 7 of HUT-78 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50219335(CHEMBL11511)
Affinity DataIC50:  4.88E+3nMAssay Description:Inhibition of human Phosphodiesterase 7 of HUT-78 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent dopamine transporter(Homo sapiens (Human))
Paradigm Therapeutics

Curated by ChEMBL
LigandPNGBDBM50183656((R)-1-(2-(dimethylamino)-1-(4-methoxyphenyl)ethyl)...)
Affinity DataIC50:  4.90E+3nMAssay Description:Inhibition of dopamine reuptake at human recombinant dopamine transporterMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed