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LigandPNGBDBM50201921(2-Biphenyl-4-yl-6-fluoro-3-hydroxy-quinoline-4-car...)
Affinity DataIC50: 5nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201923(3-hydroxy-2-(4'-hydroxy-biphenyl-4-yl)-quinoline-4...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201945(6-fluoro-3-hydroxy-2-(4-phenoxyphenyl)quinoline-4-...)
Affinity DataIC50: 6nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201905(3-hydroxy-2-(4-phenoxyphenyl)quinoline-4-carboxyli...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201919(6-fluoro-3-hydroxy-2-(4'-hydroxy-biphenyl-4-yl)-qu...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201925(2-BIPHENYL-4-YL-6-FLUORO-3-METHYL-QUINOLINE-4-CARB...)
Affinity DataIC50: 7nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201949(2-biphenyl-4-yl-3-hydroxy-quinoline-4-carboxylic a...)
Affinity DataIC50: 10nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201918(3-amino-2-biphenyl-4-yl-6-fluoro-quinoline-4-carbo...)
Affinity DataIC50: 12nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201939(6-fluoro-3-hydroxy-2-(4-(phenylthio)phenyl)quinoli...)
Affinity DataIC50: 18nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201900(6-bromo-2-(4-chlorophenyl)-3-hydroxyquinoline-4-ca...)
Affinity DataIC50: 211nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201940(2-(4-chlorophenyl)-3-hydroxy-6-methylquinoline-4-c...)
Affinity DataIC50: 217nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201913(2-(4-chlorophenyl)-3-hydroxy-6-(trifluoromethyl)qu...)
Affinity DataIC50: 270nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201934(2-(4-chlorophenyl)-6-fluoro-3-hydroxyquinoline-4-c...)
Affinity DataIC50: 312nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C19(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of human CYP2C19More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201930(6-fluoro-3-hydroxy-2-(4-hydroxyphenyl)quinoline-4-...)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 1A2(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human CYP1A2More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201892(2-(4-chlorophenyl)-3-hydroxy-6-(trifluoromethoxy)q...)
Affinity DataIC50: 4.00E+3nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201920(2-(4-chlorophenyl)-3-hydroxy-6,8-dimethylquinoline...)
Affinity DataIC50: 4.90E+3nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C9(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of human CYP2C9More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2C8(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 9.00E+3nMAssay Description:Inhibition of human CYP2C8More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201927(3-hydroxy-2-phenylquinoline-4-carboxylic acid | CH...)
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2D6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human CYP2D6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201936(2-(4-chlorophenyl)-3-hydroxy-7-methylquinoline-4-c...)
Affinity DataIC50: 1.70E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 2A6(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 2.00E+4nMAssay Description:Inhibition of human CYP2A6More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50: 2.60E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201897(3-hydroxy-7,8-dimethyl-2-(4-(trifluoromethyl)pheny...)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201931(6-bromo-2-(4-chlorophenyl)-3-hydroxy-8-methylquino...)
Affinity DataIC50: 4.10E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201909(2-(4-chlorophenyl)-3-hydroxy-6-methoxyquinoline-4-...)
Affinity DataIC50: 4.30E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201898(2-(4-chlorophenyl)-3-hydroxy-5-methylquinoline-4-c...)
Affinity DataIC50: 5.10E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCytochrome P450 3A4(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201901(2-(4-chlorophenyl)-3-hydroxy-8-phenylquinoline-4-c...)
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human CYP3A4More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201914(2-(4-bromophenyl)-3-hydroxy-7,8-dimethylquinoline-...)
Affinity DataIC50: 5.60E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50324667(TBC-1269 | 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of P-selectin in human HL-60 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin glycoprotein ligand 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50324667(TBC-1269 | 1,6-bis[3-(3-carboxymethylphenyl)-4-(2-...)
Affinity DataIC50: 7.00E+4nMAssay Description:Inhibition of P-selectin-mediated adhesion of HL60 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201902(2-(4-chlorophenyl)-3-hydroxy-7,8-dimethylquinoline...)
Affinity DataIC50: 7.20E+4nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin glycoprotein ligand 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201916(8-sec-butyl-2-(4-chlorophenyl)-3-hydroxyquinoline-...)
Affinity DataIC50: 7.50E+4nMAssay Description:Inhibition of P-selectin-mediated adhesion of HL60 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201966(2-(benzo[b]thiophen-3-ylmethyl)-3-hydroxy-7,8,9,10...)
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201959(2-(2-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobe...)
Affinity DataIC50: 1.23E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201978(2-(4-chlorophenylamino)-3-hydroxy-8-(trifluorometh...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201984(2-(4-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobe...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin glycoprotein ligand 1(Human)
Wyeth Research

Curated by ChEMBL
LigandPNGBDBM50201931(6-bromo-2-(4-chlorophenyl)-3-hydroxy-8-methylquino...)
Affinity DataIC50: 1.25E+5nMAssay Description:Inhibition of P-selectin-mediated adhesion of HL60 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201933(2-(4-chlorophenyl)-3-hydroxy-8-(trifluoromethoxy)q...)
Affinity DataIC50: 1.30E+5nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201926(8-bromo-2-(4-chlorophenyl)-3-hydroxyquinoline-4-ca...)
Affinity DataIC50: 1.32E+5nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201946(2-(4-chlorophenyl)-3-hydroxy-6-(thiophen-3-yl)quin...)
Affinity DataIC50: 1.34E+5nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201941(6-(4-carboxyphenyl)-2-(4-chlorophenyl)-3-hydroxyqu...)
Affinity DataIC50: 1.35E+5nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201938(2-(4-chlorophenyl)-3-hydroxy-8-trifluoromethylquin...)
Affinity DataIC50: 1.36E+5nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP-selectin(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50201983(2-(3-chlorobenzyl)-3-hydroxy-7,8,9,10-tetrahydrobe...)
Affinity DataIC50: 1.38E+5nMAssay Description:Inhibition of P-Selectin by Biacore assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50201895(8-chloro-2-(4-chlorophenyl)-3-hydroxyquinoline-4-c...)
Affinity DataIC50: 1.41E+5nMAssay Description:Inhibition of human recombinant DHOD expressed in Escherichia coliMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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