Compile Data Set for Download or QSAR
Report error Found 1412 with Last Name = 'beno' and Initial = 'd'
TargetDipeptidyl peptidase 4(Human)
Abbott Laboratories

LigandPNGBDBM15526(N-{[(3S,5S)-5-(1,3-thiazolidin-3-ylcarbonyl)pyrrol...)
Affinity DataAssay Description:The DPP activity resulted in the formation of the fluorescent product amidomethylcoumarin (AMC), which was monitored by excitation at 355 nm and meas...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19368(1-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50:  56nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19369(1-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50: >1.00E+4nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19370(3-tert-butyl-1-(4-{2,4-diamino-6-[(benzyloxy)methy...)
Affinity DataEC50:  7nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19371(3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50:  88nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19372(1-benzyl-3-(4-{2,4-diamino-6-[(benzyloxy)methyl]py...)
Affinity DataEC50:  34nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19373(3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50:  10nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGrowth hormone secretagogue receptor type 1(Human)
Abbott Laboratories

LigandPNGBDBM19374(3-(4-{2,4-diamino-6-[(benzyloxy)methyl]pyrimidin-5...)
Affinity DataEC50:  7nMpH: 7.4 T: 2°CAssay Description:Specific binding was determined by incubation of membranes from GHS-R1a transfected CHO-K cells with 125I-His9-ghrelin in the presence of increasing ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetDihydrofolate reductase(Human)
Abbott Laboratories

LigandPNGBDBM19352(6-ethyl-5-{1-[(4-methanesulfonylphenyl)methyl]-1H-...)
Affinity DatapH: 7.3 T: 2°CAssay Description:DHFR activity was determined by measuring the rate of depletion of NADPH, monitored at 340 nm, with a Beckman DU-7400 spectrophotometer. More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453078(CHEMBL4215254)
Affinity DataEC50:  0.00700nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2b assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453100(A-1325912.0 | ABT-530 | Pibrentasvir)
Affinity DataEC50:  0.00190nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2b assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453101(CHEMBL4208591)
Affinity DataEC50:  0.481nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 3a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453102(CHEMBL4206465)
Affinity DataEC50:  0.316nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 4a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453103(CHEMBL4218872)
Affinity DataEC50:  0.00100nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 5a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453104(CHEMBL3915742)
Affinity DataEC50:  0.151nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453105(CHEMBL3960757)
Affinity DataEC50:  0.00600nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 4a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453105(CHEMBL3960757)
Affinity DataEC50:  0.152nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453106(CHEMBL4215923)
Affinity DataEC50:  0.183nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453107(CHEMBL4215241)
Affinity DataEC50:  0.330nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453108(CHEMBL4202479)
Affinity DataEC50:  0.0750nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453109(CHEMBL4205352)
Affinity DataEC50:  0.00300nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days by luciferase reporter gene assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453107(CHEMBL4215241)
Affinity DataEC50:  0.00700nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days by luciferase reporter gene assa...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453110(CHEMBL3127327)
Affinity DataEC50:  0.136nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days by luciferase reporter gene assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453111(CHEMBL4208073)
Affinity DataEC50:  0.0480nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453112(CHEBI:85183 | ABT-267 | Ombitasvir)
Affinity DataEC50:  0.00430nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2b assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453113(CHEMBL4210254)
Affinity DataEC50:  0.0110nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 3a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.0130nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 4a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453113(CHEMBL4210254)
Affinity DataEC50:  0.00600nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 5a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453115(CHEMBL4203712)
Affinity DataEC50:  0.0100nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 6a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453109(CHEMBL4205352)
Affinity DataEC50:  0.00400nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 6a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453116(CHEMBL4215187)
Affinity DataEC50:  0.00500nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 5a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453117(CHEMBL4211486)
Affinity DataEC50:  0.00900nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 6a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453112(CHEBI:85183 | ABT-267 | Ombitasvir)
Affinity DataEC50:  0.0120nMAssay Description:Inhibition of HCV genotype 1b Con1 NS5A expressed in HuH7 cell infected HCV genotype 2a assessed as decrease in viral replication after 3 days by luc...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453116(CHEMBL4215187)
Affinity DataEC50:  0.522nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453109(CHEMBL4205352)
Affinity DataEC50:  0.138nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453113(CHEMBL4210254)
Affinity DataEC50:  0.337nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453118(CHEMBL4204257)
Affinity DataEC50:  0.126nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453101(CHEMBL4208591)
Affinity DataEC50:  1.51nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453115(CHEMBL4203712)
Affinity DataEC50:  0.132nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453114(CHEMBL4211348)
Affinity DataEC50:  0.230nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453119(CHEMBL4203054)
Affinity DataEC50:  0.279nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453120(CHEMBL4203574)
Affinity DataEC50:  0.354nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453105(CHEMBL3960757)
Affinity DataEC50:  0.268nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453121(CHEMBL4215679)
Affinity DataEC50:  0.354nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetGenome polyprotein(HCV)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453112(CHEBI:85183 | ABT-267 | Ombitasvir)
Affinity DataEC50:  0.0560nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1b Con1 assessed as decrease in viral replication after 3 days in presence of 40% human plasma ...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453100(A-1325912.0 | ABT-530 | Pibrentasvir)
Affinity DataEC50:  0.0640nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453116(CHEMBL4215187)
Affinity DataEC50:  0.220nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453118(CHEMBL4204257)
Affinity DataEC50:  0.0780nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453106(CHEMBL4215923)
Affinity DataEC50:  0.0760nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
TargetNonstructural protein 5A(Hepacivirus C)
Abbvie

Curated by ChEMBL
LigandPNGBDBM50453115(CHEMBL4203712)
Affinity DataEC50:  0.213nMAssay Description:Inhibition of NS5A in HuH7 cell infected HCV genotype 1a H77 assessed as decrease in viral replication after 3 days in presence of 40% human plasma b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails Article
PubMed
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