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TargetAlternative oxidase, mitochondrial(Trypanosoma brucei brucei)
University of Sussex

Curated by ChEMBL
LigandPNGBDBM50459778(Ascofuranone | US11565996, Compound Ascochlorin)
Affinity DataKi:  0.130nMAssay Description:Inhibition of Trypanosoma brucei alternative oxidase expressed in Escherichia coli FN102 using ubiquinol-1 as substrate preincubated for 2 mins follo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM85023(GR 168320 | GR-168320)
Affinity DataKi:  0.150nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM85023(GR 168320 | GR-168320)
Affinity DataKi:  0.190nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22541(Clobenpropit | N''-[(4-chlorophenyl)methyl]{[3-(1H...)
Affinity DataKi:  0.25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22530(N(alpha)-Methylhistamine | N-alpha-methylhistamine...)
Affinity DataKi:  0.390nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22904((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...)
Affinity DataKi:  0.5nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22904((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...)
Affinity DataKi:  1.25nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22530(N(alpha)-Methylhistamine | N-alpha-methylhistamine...)
Affinity DataKi:  1.99nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  1.99nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607211(CHEMBL5218456)
Affinity DataKi:  2.40nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607212(CHEMBL5220448)
Affinity DataKi:  2.40nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM7966(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Affinity DataKi:  2.51nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607222(CHEMBL5218740)
Affinity DataKi:  2.80nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22904((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...)
Affinity DataKi:  3.98nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22914(CHEMBL260374 | N-cyclohexyl-4-(1H-imidazol-5-yl)pi...)
Affinity DataKi:  3.98nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607215(CHEMBL5220463)
Affinity DataKi:  4.90nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22530(N(alpha)-Methylhistamine | N-alpha-methylhistamine...)
Affinity DataKi:  5.01nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607219(CHEMBL5220631)
Affinity DataKi:  5.20nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607218(CHEMBL5220922)
Affinity DataKi:  6.10nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607209(CHEMBL5219136)
Affinity DataKi:  8.80nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607221(CHEMBL5220083)
Affinity DataKi:  9.70nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM7966(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Affinity DataKi:  10nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607204(CHEMBL5219641)
Affinity DataKi:  12nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22884(2-[3-(1H-imidazol-5-yl)propyl]-1-(2-{[(5-methyl-1H...)
Affinity DataKi:  12.6nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607183(CHEMBL5220023)
Affinity DataKi:  13nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607178(CHEMBL5221012)
Affinity DataKi:  13nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607172(CHEMBL5220092)
Affinity DataKi:  14nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607194(CHEMBL5219400)
Affinity DataKi:  16nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607174(CHEMBL5220320)
Affinity DataKi:  18nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607179(CHEMBL5220037)
Affinity DataKi:  19nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22884(2-[3-(1H-imidazol-5-yl)propyl]-1-(2-{[(5-methyl-1H...)
Affinity DataKi:  19.9nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607201(CHEMBL5218904)
Affinity DataKi:  24nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM7966(2-(1H-imidazol-4-yl)ethan-1-amine | CHEMBL544208 |...)
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22904((2R)-1-(1H-imidazol-5-yl)propan-2-amine | (R)-alph...)
Affinity DataKi:  25.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607207(CHEMBL5220458)
Affinity DataKi:  27nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607193(CHEMBL5220040)
Affinity DataKi:  27nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607171(CHEMBL5219498)
Affinity DataKi:  27nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607200(CHEMBL5220510)
Affinity DataKi:  28nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607190(CHEMBL5220499)
Affinity DataKi:  31nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607191(CHEMBL5219259)
Affinity DataKi:  37nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607199(CHEMBL5218678)
Affinity DataKi:  38nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607184(CHEMBL5221108)
Affinity DataKi:  39nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607189(CHEMBL5220688)
Affinity DataKi:  39nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607188(CHEMBL5219916)
Affinity DataKi:  44nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607210(CHEMBL5219878)
Affinity DataKi:  46nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607185(CHEMBL5219402)
Affinity DataKi:  47nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607173(CHEMBL5220400)
Affinity DataKi:  58nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetNectin-4(Homo sapiens)
Bicycletx

Curated by ChEMBL
LigandPNGBDBM50607195(CHEMBL5220633)
Affinity DataKi:  59nMAssay Description:Displacement of tracer from C-terminal FLAG-tagged human Nectin-4 (32 to 349 residues) expressed in baculovirus infected sf9 cells assessed as inhibi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetHrh3 protein(RAT)
Glaxo Research & Development

Curated by PDSP Ki Database
LigandPNGBDBM22888(1-[4-(1H-imidazol-5-yl)butyl]-3-methylthiourea | B...)
Affinity DataKi:  63.1nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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