BindingDB PrimarySearch

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577226(CHEMBL4872989)

IC50: 15nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577227(CHEMBL4856425)

IC50: 25nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577229(CHEMBL4877651)

IC50: 32nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042251(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.5]dec-1-en-3-y...)

IC50: 155nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042234(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-y...)

IC50: 190nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577228(CHEMBL4859498)

IC50: 390nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577231(CHEMBL4868159)

IC50: 1.01E+3nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042250(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-ylmeth...)

IC50: 7.75E+3nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042236(4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)

IC50: 8.65E+3nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042263(4'-(4-Oxo-2-phenyl-1,3-diaza-spiro[4.4]non-1-en-3-...)

IC50: >1.00E+4nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank antibodypedia GoogleScholar

Type-1 angiotensin II receptor(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577230(CHEMBL4854916)

IC50: 1.00E+4nMAssay Description:Antagonist activity at human AT1 overexpressed in CHO-K1 cells in presence of 10 nM [Val5-angiotensin II measured after 90 mins by HTRF based IP-one ...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50130262(2,3,4,9-Tetrahydro-1H-beta-carboline | CHEMBL26923...)

EC50: 7.40E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid PDB Patents Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50404775(CHEMBL31888)

EC50: 1.94E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50580566(CHEMBL3304960)

EC50: 6.70E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

Purchase PC cid PC sid

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM14777((2R,8R)-2-(2H-1,3-benzodioxol-5-yl)-6-methyl-3,6,1...)

EC50: 5.00E+3nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank MCE
MMDB PC cid PC sid PDB Patents Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM25761(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)

EC50: 3.20E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG PC cid PC sid PDB Patents Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50067133(1-(2-(2-hydroxy-3-(propylamino)propoxy)phenyl)-3-p...)

EC50: 4.70E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG PC cid PC sid PDB Patents Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM60973((2R)-1-(1-naphthalenyloxy)-3-(propan-2-ylamino)-2-...)

EC50: 4.00E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

Purchase DrugBank MCE
KEGG PC cid PC sid Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50246936((-)-(S)-Propranolol | 1-(ISOPROPYLAMINO)-3-(1-NAPH...)

EC50: 7.20E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL MCE
KEGG MMDB PC cid PC sid PDB Patents Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50580567(CHEMBL5070124)

EC50: >1.00E+5nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50580568(CHEMBL5088115)

EC50: 8.30E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50580569(CHEMBL5083628)

EC50: 5.20E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50061966(CHEMBL139737 | Isopropyl-[3-(naphthalen-1-yloxy)-p...)

EC50: 5.00E+4nMAssay Description:Agonist activity at in human TLX LBD expressed in human HEK293T cells coexpressing Gal4-VP 16 assessed as increase in reporter activity measured afte...More data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM25761(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)

EC50: 3.20E+4nMAssay Description:Agonist activity at full length TLX activating element expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as dec...More data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG PC cid PC sid PDB Patents Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50130262(2,3,4,9-Tetrahydro-1H-beta-carboline | CHEMBL26923...)

EC50: >1.00E+5nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid PDB Patents Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50404775(CHEMBL31888)

EC50: 4.30E+4nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair

Purchase CHEMBL PC cid PC sid Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM50580566(CHEMBL3304960)

Purchase PC cid PC sid

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM25761(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)

EC50: 3.70E+4nMAssay Description:Agonist activity at TAE expressed in human HEK293T cells coexpressing human full-length TLX/Gal4-VP 16 assessed as renilla luciferase reporter activi...More data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG PC cid PC sid PDB Patents Similars

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577230(CHEMBL4854916)

EC50: 7.50E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577229(CHEMBL4877651)

EC50: 8.14E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577228(CHEMBL4859498)

EC50: 6.39E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042250(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-ylmeth...)

EC50: 2.42E+4nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577227(CHEMBL4856425)

EC50: 550nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50577226(CHEMBL4872989)

EC50: 68nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042251(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.5]dec-1-en-3-y...)

EC50: 860nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042236(4'-(2-Benzyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-...)

EC50: 6.58E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042234(4'-(2-Butyl-4-oxo-1,3-diaza-spiro[4.4]non-1-en-3-y...)

EC50: 1.49E+3nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50049186((S)-3-Methyl-2-{pentanoyl-[2'-(1H-tetrazol-5-yl)-b...)

EC50: 1.60E+4nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Purchase CHEMBL MCE
PC cid PC sid Patents Similars

PDB NCI pathway Reactome pathway KEGG
UniProtKB/SwissProt
DrugBank GoogleScholar

Nuclear receptor subfamily 2 group E member 1(Homo sapiens)
Goethe-University Frankfurt

Curated by ChEMBL

BDBM25761(Anapriline | Avlocardyl | CHEMBL27 | PROPANOLOL(-)...)

Kd: 500nMAssay Description:Binding affinity to TLX LBD expressed in His6-tagged Escherichia coli Rosetta assessed as binding constant measured after 300 sec at 200 mM by isothe...More data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL DrugBank MCE
KEGG PC cid PC sid PDB Patents Similars

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50042235(2-butyl-3-{[2'-(1H-tetrazol-5-yl)[1,1'-biphenyl]-4...)

EC50: 410nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Purchase CHEMBL MCE
KEGG PC cid PC sid Patents Similars

Leukotriene B4 receptor 2(Homo sapiens (Human))
Fraunhofer Institute for Translational Medicine and Phamacology ITMP

Curated by ChEMBL

BDBM50240609(2-Ethoxy-3-[2'-(1H-tetrazol-5-yl)-biphenyl-4-ylmet...)

EC50: 1.50E+4nMAssay Description:Agonist activity at human BLT2 overexpressed in CHO-K1 cells assessed as accumulation of inositol monophosphate measured after 90 mins by HTRF assayMore data for this Ligand-Target Pair

Purchase ChEBI
CHEMBL KEGG PC cid PC sid Patents Similars