Report error Found 696 with Last Name = 'bolchi' and Initial = 'c'
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.01E+4nMAssay Description:Partial agonist activity at human alpha4beta2 nAChR expressed in GH4CL cells by whole-cell patch clamp methodMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 2.40E+3nMAssay Description:Agonist activity at wild type human alpha4beta2 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysi...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 3.80E+3nMAssay Description:Agonist activity at wild type human alpha4beta2 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysi...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 2.60E+3nMAssay Description:Agonist activity at wild type human alpha4beta2 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysi...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 8.70E+3nMAssay Description:Partial agonist activity at human alpha3beta4 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysiol...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.70E+4nMAssay Description:Partial agonist activity at human alpha3beta4 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysiol...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-3/beta-4(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.90E+4nMAssay Description:Partial agonist activity at human alpha3beta4 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysiol...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 5nMAssay Description:Partial agonist activity at human alpha4beta2 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysiol...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Partial agonist activity at human alpha4beta2 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysiol...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.40E+4nMAssay Description:Partial agonist activity at human alpha4beta2 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysiol...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.01E+4nMAssay Description:Partial agonist activity at human alpha4beta2 transfected in rat GH4-C1 cells at holding potential of -70 mV by whole cell patch clamp electrophysiol...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 2.34E+3nMAssay Description:Partial agonist activity at high sensitivity isoform human (alpha4)2(beta2)3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acet...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 129nMAssay Description:Partial agonist activity at high sensitivity isoform human (alpha4)2(beta2)3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acet...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 799nMAssay Description:Partial agonist activity at high sensitivity isoform human (alpha4)2(beta2)3 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acet...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 3.00E+3nMAssay Description:Partial agonist activity at low sensitivity isoform human (alpha4)3(beta2)2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acety...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 2.18E+4nMAssay Description:Partial agonist activity at low sensitivity isoform human (alpha4)3(beta2)2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acety...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 4.80E+3nMAssay Description:Partial agonist activity at low sensitivity isoform human (alpha4)3(beta2)2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acety...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.85E+4nMAssay Description:Partial agonist activity at low sensitivity isoform human (alpha4)3(beta2)2 nAChR expressed in Xenopus laevis oocytes assessed as inhibition of acety...More data for this Ligand-Target Pair
Affinity DataKd: 0.300nMAssay Description:Displacement of [125I]alpha-bungarotoxin from alpha7 nAChR in Sprague-Dawley rat cerebral cortex by beta countingMore data for this Ligand-Target Pair
Affinity DataKd: 0.324nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostate assessed as inhibition of noradrenaline-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 50.1nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostate assessed as inhibition of noradrenaline-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 2.82nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostate assessed as inhibition of noradrenaline-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 0.912nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostate assessed as inhibition of noradrenaline-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 1.20nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostate assessed as inhibition of noradrenaline-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 39.8nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostate assessed as inhibition of noradrenaline-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 0.105nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostatic vas deferens assessed as inhibition of noradrenaline-induced contractions...More data for this Ligand-Target Pair
Affinity DataKd: 166nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostatic vas deferens assessed as inhibition of noradrenaline-induced contractions...More data for this Ligand-Target Pair
Affinity DataKd: 1.70nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostatic vas deferens assessed as inhibition of noradrenaline-induced contractions...More data for this Ligand-Target Pair
Affinity DataKd: 0.275nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostatic vas deferens assessed as inhibition of noradrenaline-induced contractions...More data for this Ligand-Target Pair
Affinity DataKd: 28.8nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostatic vas deferens assessed as inhibition of noradrenaline-induced contractions...More data for this Ligand-Target Pair
Affinity DataKd: 53.7nMAssay Description:Antagonist activity at alpha1A adrenoceptor in Sprague-Dawley rat prostatic vas deferens assessed as inhibition of noradrenaline-induced contractions...More data for this Ligand-Target Pair
Affinity DataKd: 0.676nMAssay Description:Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 15.8nMAssay Description:Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 0.263nMAssay Description:Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 8.91nMAssay Description:Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 2.75nMAssay Description:Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 16.6nMAssay Description:Antagonist activity at alpha1B adrenoceptor in Sprague-Dawley rat spleen assessed as inhibition of phenylephrine-induced contractions after 30 minsMore data for this Ligand-Target Pair
Affinity DataKd: 0.631nMAssay Description:Antagonist activity at alpha1D adrenoceptor in Sprague-Dawley rat thoracic aorta assessed as inhibition of noradrenaline-induced contractions after 3...More data for this Ligand-Target Pair
Affinity DataKd: 51.3nMAssay Description:Antagonist activity at alpha1D adrenoceptor in Sprague-Dawley rat thoracic aorta assessed as inhibition of noradrenaline-induced contractions after 3...More data for this Ligand-Target Pair
Affinity DataKd: 11.8nMAssay Description:Antagonist activity at alpha1D adrenoceptor in Sprague-Dawley rat thoracic aorta assessed as inhibition of noradrenaline-induced contractions after 3...More data for this Ligand-Target Pair
Affinity DataKd: 3.02nMAssay Description:Antagonist activity at alpha1D adrenoceptor in Sprague-Dawley rat thoracic aorta assessed as inhibition of noradrenaline-induced contractions after 3...More data for this Ligand-Target Pair
Affinity DataKd: 9.33nMAssay Description:Antagonist activity at alpha1D adrenoceptor in Sprague-Dawley rat thoracic aorta assessed as inhibition of noradrenaline-induced contractions after 3...More data for this Ligand-Target Pair
Affinity DataKd: 5.75nMAssay Description:Antagonist activity at alpha1D adrenoceptor in Sprague-Dawley rat thoracic aorta assessed as inhibition of noradrenaline-induced contractions after 3...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 4.40E+3nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding potential of -70 ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 400nMAssay Description:Agonist activity at human alpha4beta2 nAChR high affinity form expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holdin...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 13nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding potential of -70 ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.00E+5nMAssay Description:Agonist activity at human alpha4beta2 nAChR in (alpha4)3(beta2)2 stoichiometry formMore data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 300nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding potential of -70 ...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 1.00E+5nMAssay Description:Agonist activity at human alpha4beta2 nAChR low affinity form expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding...More data for this Ligand-Target Pair
TargetNeuronal acetylcholine receptor subunit alpha-4/beta-2(Human)
University of Milan
Curated by ChEMBL
University of Milan
Curated by ChEMBL
Affinity DataEC50: 0.270nMAssay Description:Agonist activity at human alpha4beta2 nAChR expressed in rat GH4C1 cells assessed as induction of peak current amplitude at holding potential of -70 ...More data for this Ligand-Target Pair
