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TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50475328(CHEMBL414782)
Affinity DataKi:  0.00500nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50475327(CHEMBL410653)
Affinity DataKi:  0.00700nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50475330(CHEMBL442297)
Affinity DataKi:  0.0200nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.0210nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50475333(CHEMBL264846)
Affinity DataKi:  0.0220nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50475331(CHEMBL411649)
Affinity DataKi:  0.0250nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50475325(CHEMBL262544)
Affinity DataKi:  0.0320nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50475329(CHEMBL263588)
Affinity DataKi:  0.0480nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50004178(Nociceptin | Nociceptin/orphanin FQ | ORPHANIN FQ)
Affinity DataKi:  0.0490nMAssay Description:Binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.0680nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.0760nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50475326(CHEMBL410145)
Affinity DataKi:  0.129nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50472747(CHEMBL414767)
Affinity DataKi:  0.129nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM85822(Demethyl-AMPA | OFQ/N | OFQ/N (1-11) | OFQ/N (1-11...)
Affinity DataKi:  0.140nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062051(1-Dimethylcarbamoyl-6-(4-fluoro-phenyl)-3-[4-(2-me...)
Affinity DataKi:  0.150nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062066(3-[4-(2-Methyl-imidazo[4,5-c]pyridin-1-ylmethyl)-b...)
Affinity DataKi:  0.190nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50475332(CHEMBL413944)
Affinity DataKi:  0.240nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Mouse)
Section of Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.360nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50286027(6-(4-Fluoro-phenyl)-3-[[(Z)-hydroxyimino]-((R)-3-p...)
Affinity DataKi:  0.370nMAssay Description:Binding affinity for platelet activating factor receptor using [3H]-PAF in rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails Article

TargetNociceptin receptor(Mouse)
Section of Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.380nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50048485((S)-4-Methyl-2-{methyl-[4-(2-methyl-imidazo[4,5-c]...)
Affinity DataKi:  0.400nMAssay Description:The compound was evaluated for its binding affinity against PAF receptor in rabbit plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50048485((S)-4-Methyl-2-{methyl-[4-(2-methyl-imidazo[4,5-c]...)
Affinity DataKi:  0.400nMAssay Description:The compound was evaluated for its binding affinity against PAF receptor in rabbit plateletMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Human)
University of Ferrara

Curated by ChEMBL
LigandPNGBDBM50472746(CHEMBL411621)
Affinity DataKi:  0.417nMAssay Description:Receptor binding affinity for recombinant human N/OFQ peptide receptor (NOP) expressed in chinese hamster ovary cellsMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062069(4-Methoxy-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-y...)
Affinity DataKi:  0.510nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Pig)
Section of Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.580nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038757(6-Bromo-3-((R)-2-pyridin-3-yl-thiazolidine-4-carbo...)
Affinity DataKi:  0.600nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062056(1-Dimethylcarbamoyl-3-{2-[4-(2-methyl-imidazo[4,5-...)
Affinity DataKi:  0.630nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062101(4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataKi:  0.630nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetNociceptin receptor(Mouse)
Section of Pharmacology

Curated by PDSP Ki Database
LigandPNGBDBM86660(OFQ/N UFP-102)
Affinity DataKi:  0.650nMMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062061(1-(3,3-Dimethyl-2-oxo-butyl)-3-[4-(2-methyl-imidaz...)
Affinity DataKi:  0.670nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50285986(2-[6-(4-Fluoro-phenyl)-3-(3-pyridin-3-yl-1H-pyrrol...)
Affinity DataKi:  0.700nMAssay Description:Tested in vitro for antagonistic activity to displace [3H]-PAF from rabbit platelet membrane PAF receptorsMore data for this Ligand-Target Pair
In DepthDetails Article

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062045(6-Benzofuran-2-yl-1-dimethylcarbamoyl-3-[4-(2-meth...)
Affinity DataKi:  0.780nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038809(3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-ind...)
Affinity DataKi:  0.800nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062082(4-Methyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-yl...)
Affinity DataKi:  0.820nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062113(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  0.850nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062064(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  0.860nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062092((4,7-Dimethyl-1H-indol-3-yl)-[4-(2-methyl-imidazo[...)
Affinity DataKi:  0.870nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062106(4-Chloro-3-[4-(2-methyl-imidazo[4,5-b]pyridin-1-yl...)
Affinity DataKi:  0.900nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062118(4-Ethyl-3-[4-(2-methyl-imidazo[4,5-c]pyridin-1-ylm...)
Affinity DataKi:  0.910nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062048(1-Dimethylcarbamoyl-3-[4-(2-methyl-benzoimidazol-1...)
Affinity DataKi:  0.920nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062098(1-Dimethylcarbamoyl-3-[4-(2-methyl-imidazo[4,5-c]p...)
Affinity DataKi:  0.950nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038750(3-((R)-2-Pyridin-3-yl-thiazolidine-4-carbonyl)-ind...)
Affinity DataKi:  1nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038806(6-Chloro-3-((R)-2-pyridin-3-yl-thiazolidine-4-carb...)
Affinity DataKi:  1nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062054(4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataKi:  1nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062054(4-Ethynyl-3-[3-fluoro-4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataKi:  1nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038834(6-Benzoyl-3-((R)-2-pyridin-3-yl-thiazolidine-4-car...)
Affinity DataKi:  1nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038792(6-Benzyloxy-3-((R)-2-pyridin-3-yl-thiazolidine-4-c...)
Affinity DataKi:  1nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50062091(1-(2-Ethoxy-ethyl)-3-[4-(2-methyl-imidazo[4,5-c]py...)
Affinity DataKi:  1.10nMAssay Description:Binding potency against Platelet activating factor (PAF) receptor using [3H]-C18-PAF as radioligand on rabbit platelet membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038777((7-Benzyloxy-1H-indol-3-yl)-((R)-2-pyridin-3-yl-th...)
Affinity DataKi:  1.10nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetPlatelet-activating factor receptor(Guinea pig)
Abbott Laboratories

Curated by ChEMBL
LigandPNGBDBM50038780(CHEMBL64428 | [3-((R)-2-Pyridin-3-yl-thiazolidine-...)
Affinity DataKi:  1.20nMAssay Description:Antagonist activity against platelet activating factor (PAF) receptor in rabbit platelet membranes using [3H]C18-PAF as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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