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LigandPNGBDBM50616571(CHEMBL5419752)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616591(CHEMBL5436282)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616573(CHEMBL5420931)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616553(CHEMBL5424727)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616586(CHEMBL5407842)
Affinity DataEC50:  1.24E+4nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616597(CHEMBL5420539)
Affinity DataEC50:  3.10E+3nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616598(CHEMBL5440906)
Affinity DataEC50:  3.73E+4nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616575(CHEMBL5395857)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616559(CHEMBL5439318)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616590(CHEMBL5433765)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616580(CHEMBL5396530)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616549(CHEMBL5424664)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616557(CHEMBL5437142)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616551(CHEMBL5404038)
Affinity DataEC50:  7.45E+4nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616555(CHEMBL5395679)
Affinity DataEC50:  1.19E+4nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616577(CHEMBL5398061)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616584(CHEMBL5433154)
Affinity DataEC50:  4.42E+4nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616581(CHEMBL5409881)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616567(CHEMBL5402861)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616569(CHEMBL5420020)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616561(CHEMBL5432770)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616592(CHEMBL5425202)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616587(CHEMBL5397521)
Affinity DataEC50:  1.25E+4nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616594(CHEMBL5440763)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616545(CHEMBL5405279)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616582(CHEMBL5395619)
Affinity DataEC50:  8.00E+3nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616596(CHEMBL5422706)
Affinity DataEC50:  2.95E+4nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616563(CHEMBL5397659)
Affinity DataEC50: >1.00E+5nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
LigandPNGBDBM50616588(CHEMBL5399204)
Affinity DataEC50:  2.19E+4nMAssay Description:Agonist activity at human TRPV1 expressed in SH-SY5Y cells measured for 25 mins in presence of capsaicin by fluorescence based microplate reader anal...More data for this Ligand-Target Pair
In Depth
Date in BDB:
12/13/2024
Entry Details
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580099(CHEMBL5078071)
Affinity DataIC50: 850nMAssay Description:Inhibition of telomerase in human HCT-116 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580099(CHEMBL5078071)
Affinity DataIC50: 900nMAssay Description:Inhibition of telomerase in human COLO 205 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154420((Z)-4-(1-Benzyl-1H-indol-2-yl)-2-hydroxy-4-oxo-but...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154408(CHEMBL1673089 | CHEMBL186820 | (Z)-4-(1-Benzyl-1H-...)
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154411((Z)-4-(1-Ethyl-1H-indol-2-yl)-2-hydroxy-4-oxo-but-...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154406((Z)-2-Hydroxy-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]in...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154419((Z)-4-(5-Benzyl-5H-[1,3]dioxolo[4,5-f]indol-6-yl)-...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154416((Z)-2-Hydroxy-4-(1-methyl-1H-indol-3-yl)-4-oxo-but...)
Affinity DataIC50: 2.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580099(CHEMBL5078071)
Affinity DataIC50: 2.20E+3nMAssay Description:Inhibition of telomerase in human HT-29 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154417((Z)-2-Hydroxy-4-(5-methyl-5H-[1,3]dioxolo[4,5-f]in...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154410((Z)-4-(1-Ethyl-1H-indol-3-yl)-2-hydroxy-4-oxo-but-...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154414((Z)-4-(5-Ethyl-5H-[1,3]dioxolo[4,5-f]indol-7-yl)-2...)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580099(CHEMBL5078071)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of telomerase in human SW-620 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580097(CHEMBL5090701)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of telomerase in human HCT-116 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetIntegrase(Human immunodeficiency virus type 1)
Università

Curated by ChEMBL
LigandPNGBDBM50154413((Z)-4-(5-Ethyl-5H-[1,3]dioxolo[4,5-f]indol-6-yl)-2...)
Affinity DataIC50: 5.00E+3nMAssay Description:Inhibitory concentration against HIV-1 integrase mediated strand transfer reactionMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50539865(CHEMBL4638841)
Affinity DataIC50: 5.20E+3nMAssay Description:Inhibition of telomerase in human PC3 cell-free extracts incubated for 48 hrs by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50539853(CHEMBL4634543)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of telomerase in human PC3 cell-free extracts incubated for 48 hrs by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/12/2021
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580098(CHEMBL5075948)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of telomerase in human HCT-116 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580100(CHEMBL5089227)
Affinity DataIC50: 5.70E+3nMAssay Description:Inhibition of telomerase in human HCT-116 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580097(CHEMBL5090701)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of telomerase in human COLO 205 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
TargetTelomerase reverse transcriptase(Human)
Institute of Biomedical Chemistry

Curated by ChEMBL
LigandPNGBDBM50580098(CHEMBL5075948)
Affinity DataIC50: 5.90E+3nMAssay Description:Inhibition of telomerase in human COLO 205 cells by TRAP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
3/4/2023
Entry Details Article
PubMed
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