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TargetAndrogen receptor(Human)
Novartis Institutes For Biomedical Research

Curated by ChEMBL
LigandPNGBDBM50057651(CHEMBL3326454)
Affinity DataIC50:  0.700nMAssay Description:Displacement of [3H]DHT from androgen receptor in human MDA-MB-435 cells after 30 minsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381517(CHEMBL2017748)
Affinity DataIC50:  4nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381530(CHEMBL2017761)
Affinity DataIC50:  6nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381510(CHEMBL2017741)
Affinity DataIC50:  10nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381513(CHEMBL2017744)
Affinity DataIC50:  11nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381513(CHEMBL2017744)
Affinity DataIC50:  12nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381510(CHEMBL2017741)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381511(CHEMBL2017742)
Affinity DataIC50:  13nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381531(CHEMBL2017762)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381527(CHEMBL2017757)
Affinity DataIC50:  14nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381512(CHEMBL2017743)
Affinity DataIC50:  15nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381509(CHEMBL2017740)
Affinity DataIC50:  16nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381485(CHEMBL2017593)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381517(CHEMBL2017748)
Affinity DataIC50:  16nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381509(CHEMBL2017740)
Affinity DataIC50:  17nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381518(CHEMBL2017751)
Affinity DataIC50:  18nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381529(CHEMBL2017760)
Affinity DataIC50:  19nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381515(CHEMBL2017746)
Affinity DataIC50:  20nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381508(CHEMBL2017618)
Affinity DataIC50:  20nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381520(CHEMBL2017753)
Affinity DataIC50:  21nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381520(CHEMBL2017753)
Affinity DataIC50:  21nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381506(CHEMBL2017616)
Affinity DataIC50:  23nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381498(CHEMBL2017606)
Affinity DataIC50:  24nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381530(CHEMBL2017761)
Affinity DataIC50:  26nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381521(CHEMBL2017754)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381507(CHEMBL2017617)
Affinity DataIC50:  26nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381528(CHEMBL2017759)
Affinity DataIC50:  27nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381511(CHEMBL2017742)
Affinity DataIC50:  30nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381502(CHEMBL2017612)
Affinity DataIC50:  30nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381527(CHEMBL2017757)
Affinity DataIC50:  31nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381480(CHEMBL2017750)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381534(CHEMBL2017765)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381519(CHEMBL2017752)
Affinity DataIC50:  31nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381505(CHEMBL2017615)
Affinity DataIC50:  32nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381531(CHEMBL2017762)
Affinity DataIC50:  32nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381478(CHEMBL2017758)
Affinity DataIC50:  34nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381532(CHEMBL2017763)
Affinity DataIC50:  34nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381524(CHEMBL2017749)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381508(CHEMBL2017618)
Affinity DataIC50:  35nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381502(CHEMBL2017612)
Affinity DataIC50:  36nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381514(CHEMBL2017745)
Affinity DataIC50:  39nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381481(CHEMBL2017588)
Affinity DataIC50:  40nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381480(CHEMBL2017750)
Affinity DataIC50:  41nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381528(CHEMBL2017759)
Affinity DataIC50:  41nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381516(CHEMBL2017747)
Affinity DataIC50:  43nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381529(CHEMBL2017760)
Affinity DataIC50:  45nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381526(CHEMBL2017756)
Affinity DataIC50:  45nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381532(CHEMBL2017763)
Affinity DataIC50:  45nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381512(CHEMBL2017743)
Affinity DataIC50:  51nMAssay Description:Displacement of [125-I]MCH from human recombinant MCHR1 expressed in CHO-K1 cell membranes after 2 hrs by scintillation proximity assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetMelanin-concentrating hormone receptor 1(Human)
Dr. Reddy'S Laboratories

Curated by ChEMBL
LigandPNGBDBM50381494(CHEMBL2017602)
Affinity DataIC50:  54nMAssay Description:Antagonist activity at human recombinant MCHR1 expressed in CHO-K1 cells assessed as inhibition of MCH-induced IP3 accumulation response preincubated...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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