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TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316314(((2R,3S,4R,5R)-5-(2-Amino-6-oxo-7-(3-(trifluoromet...)
Affinity DataKd:  7.56E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316302(((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...)
Affinity DataKd:  10nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316315(((2R,3S,4R,5R)-5-(2-Amino-7-(4-fluorobenzyl)-6-oxo...)
Affinity DataKd:  7.51E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in absence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316311(((2R,3S,4R,5R)-5-(2-Amino-7-(2-fluorobenzyl)-6-oxo...)
Affinity DataKd:  3.36E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in absence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316306(((2R,3S,4R,5R)-5-(2-Amino-7-(3-fluorobenzyl)-6-oxo...)
Affinity DataKd:  2.23E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in absence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316305(((2R,3S,4R,5R)-5-(2-amino-7-benzyl-6-oxo-1H-purin-...)
Affinity DataKd:  790nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in absence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316320(((2R,3S,4R,5R)-5-(2-Amino-7-(2-methylbenzyl)-6-oxo...)
Affinity DataKd:  6.91E+4nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316319(((2R,3S,4R,5R)-5-(2-Amino-7-(2,5-dichlorobenzyl)-6...)
Affinity DataKd:  1.73E+4nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316318(((2R,3S,4R,5R)-5-(2-Amino-7-(3-methylbenzyl)-6-oxo...)
Affinity DataKd:  1.58E+4nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316317(((2R,3S,4R,5R)-5-(2-Amino-7-(3-nitrobenzyl)-6-oxo-...)
Affinity DataKd:  1.44E+4nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316316(((2R,3S,4R,5R)-5-(2-Amino-7-(naphthalen-2-ylmethyl...)
Affinity DataKd:  9.05E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316315(((2R,3S,4R,5R)-5-(2-Amino-7-(4-fluorobenzyl)-6-oxo...)
Affinity DataKd:  8.22E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316313(((2R,3S,4R,5R)-5-(2-Amino-7-(3-methoxybenzyl)-6-ox...)
Affinity DataKd:  6.60E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316312(((2R,3S,4R,5R)-5-(2-Amino-7-(4-carboxybenzyl)-6-ox...)
Affinity DataKd:  4.59E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316311(((2R,3S,4R,5R)-5-(2-Amino-7-(2-fluorobenzyl)-6-oxo...)
Affinity DataKd:  4.39E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316310(((2R,3S,4R,5R)-5-(2-Amino-7-(2-chloro-5-fluorobenz...)
Affinity DataKd:  3.10E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316309(((2R,3S,4R,5R)-5-(2-Amino-7-(2-chlorobenzyl)-6-oxo...)
Affinity DataKd:  2.24E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316308(((2R,3S,4R,5R)-5-(2-Amino-7-(3-chlorobenzyl)-6-oxo...)
Affinity DataKd:  2.20E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316307(((2R,3S,4R,5R)-5-(2-Amino-7-(4-chlorobenzyl)-6-oxo...)
Affinity DataKd:  1.99E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316306(((2R,3S,4R,5R)-5-(2-Amino-7-(3-fluorobenzyl)-6-oxo...)
Affinity DataKd:  1.59E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316305(((2R,3S,4R,5R)-5-(2-amino-7-benzyl-6-oxo-1H-purin-...)
Affinity DataKd:  1.32E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316304(((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...)
Affinity DataKd:  7.50E+3nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetEukaryotic translation initiation factor 4E(Mouse)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50316303(((2R,3S,4R,5R)-5-(2-amino-7-methyl-6-oxo-1H-purin-...)
Affinity DataKd:  45nMAssay Description:Binding affinity to mouse eIF4E expressed in Escherichia coli by fluorescence time-synchronized titration method in presence of KKRYDREFLLGFQFIFAMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM8494((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50: 500nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133313(CHEMBL3634968)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133314(CHEMBL3634967)
Affinity DataIC50: 1.20E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133312(CHEMBL3634969)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133327(CHEMBL3634981)
Affinity DataIC50: 1.30E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM8494((2R)-2-[(4-fluoro-3-methylbenzene)sulfonamido]-N-h...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 5 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133315(CHEMBL3634966)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133311(CHEMBL3634970)
Affinity DataIC50: 1.80E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133319(CHEMBL3634962)
Affinity DataIC50: 2.10E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133306(CHEMBL3634975)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133318(CHEMBL3634963)
Affinity DataIC50: 3.20E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133320(CHEMBL3634961)
Affinity DataIC50: 3.40E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133308(CHEMBL3634973)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133310(CHEMBL3634971)
Affinity DataIC50: 3.70E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133305(CHEMBL3634976)
Affinity DataIC50: 3.90E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133304(CHEMBL3634977)
Affinity DataIC50: 4.30E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133313(CHEMBL3634968)
Affinity DataIC50: 4.40E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 5 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133307(CHEMBL3634974)
Affinity DataIC50: 4.70E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133301(CHEMBL3634980)
Affinity DataIC50: 4.80E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133327(CHEMBL3634981)
Affinity DataIC50: 5.60E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 5 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133316(CHEMBL3634965)
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133319(CHEMBL3634962)
Affinity DataIC50: 6.90E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 5 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133325(CHEMBL3634956)
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 10 mins by mobility shift protease assay using 8 uM FITC as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133311(CHEMBL3634970)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 5 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133318(CHEMBL3634963)
Affinity DataIC50: 8.00E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 5 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133312(CHEMBL3634969)
Affinity DataIC50: 8.20E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 5 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetLethal factor(Bacillus anthracis)
University of Minnesota

Curated by ChEMBL
LigandPNGBDBM50133314(CHEMBL3634967)
Affinity DataIC50: 8.90E+3nMAssay Description:Inhibition of Bacillus anthracis Lethal factor after 5 mins by FRET assayMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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