Compile Data Set for Download or QSAR
Found 4215 with Last Name = 'choi' and Initial = 'h'
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059585(CHEMBL442323 | N-CPM[D-Pro-10]Dyn A-(1-11))
Affinity DataKi:  0.0200nMAssay Description:Affinity against Opioid receptor kappa 1 was determined by measuring the inhibition of [3H]-bremazocine binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002347(CHEMBL425806 | [N-cyclopropyl methylTyr1, D-pro10]...)
Affinity DataKi:  0.0200nMAssay Description:Tested for inhibitory effect on binding of [3H]bremazocine to opioid receptor kappa in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059583(CHEMBL268818 | N-benzyl[D-Pro-10]Dyn A-(1-11) | Ph...)
Affinity DataKi:  0.0290nMAssay Description:Affinity against Opioid receptor kappa 1 was determined by measuring the inhibition of [3H]-bremazocine binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002345(CHEMBL407529 | PhCH2Tyr-Gly-Gly-Phe-Leu-Arg-Arg-ll...)
Affinity DataKi:  0.0290nMAssay Description:Tested for inhibitory effect on binding of [3H]bremazocine to opioid receptor kappa in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002346(CHEMBL384584 | [D-pro10]Dynorphin A(1-11))
Affinity DataKi:  0.0300nMAssay Description:Affinity against Opioid receptor kappa 1 was determined by measuring the inhibition of [3H]-bremazocine binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002346(CHEMBL384584 | [D-pro10]Dynorphin A(1-11))
Affinity DataKi:  0.0300nMAssay Description:Tested for inhibitory effect on binding of [3H]bremazocine to opioid receptor kappa in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50366620(RESINIFERATOXIN)
Affinity DataKi:  0.0426nMAssay Description:Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059586(CHEMBL406338 | N-allyl[D-Pro-10]Dyn A-(1-11))
Affinity DataKi:  0.0490nMAssay Description:Affinity against Opioid receptor kappa 1 was determined by measuring the inhibition of [3H]-bremazocine binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002350(CHEMBL265387 | [N-allylTyr1, D-pro10]Dynorphin A(1...)
Affinity DataKi:  0.0490nMAssay Description:Tested for inhibitory effect on binding of [3H]bremazocine to opioid receptor kappa in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50247744(CHEMBL504725 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)
Affinity DataKi:  0.0730nMAssay Description:Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50284986(CHEMBL55197 | [(R)-1-((S)-1-{(2R,3S)-3-[((S)-2-Ben...)
Affinity DataKi:  0.100nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288943(CHEMBL154519 | Quinoline-2-carboxylic acid {(R)-1-...)
Affinity DataKi:  0.113nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50052442((4-Hydroxy-3-methoxy-phenyl)-acetic acid (2R,3S,3a...)
Affinity DataKi:  0.130nMAssay Description:In vitro binding to Rat Vanilloid receptor 1 (VR1) expressing CHO cells compared to capsacinMore data for this Ligand-Target Pair
TargetProtein kinase C delta type(Homo sapiens (Human))
National Cancer Institute-Bethesda

LigandPNGBDBM92596(Sapintoxin D)
Affinity DataKi:  0.140nM ΔG°:  -54.9kJ/molepH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288941((3S,4aS,8aS)-2-((2R,3S)-2-Hydroxy-3-{(R)-2-[2-(5-h...)
Affinity DataKi:  0.151nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571836((Z)-3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbon...)
Affinity DataKi:  0.160nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288942(CHEMBL154692 | {(R)-1-[(1S,2R)-1-Benzyl-3-((3S,4aS...)
Affinity DataKi:  0.162nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288939(CHEMBL345187 | Quinoline-2-carboxylic acid {(R)-1-...)
Affinity DataKi:  0.172nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetKappa-type opioid receptor(Cavia porcellus (domestic guinea pig))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50059581(CHEMBL406893 | N,N-diCPM[D-Pro-10]Dyn A-(1-11))
Affinity DataKi:  0.190nMAssay Description:Affinity against Opioid receptor kappa 1 was determined by measuring the inhibition of [3H]-bremazocine binding to guinea pig cerebellar membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50247741(CHEMBL503101 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)
Affinity DataKi:  0.228nMAssay Description:Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(GUINEA PIG)
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002346(CHEMBL384584 | [D-pro10]Dynorphin A(1-11))
Affinity DataKi:  0.240nMAssay Description:Tested for inhibitory effect on binding of [3H]DAMGO to opioid receptor mu in guinea pig cerebellum membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50063266(6-Nitro-2-piperazin-1-yl-quinoline | 6-nitroquipaz...)
Affinity DataKi:  0.240nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetMu-type opioid receptor(Rattus norvegicus (rat))
Oregon State University

Curated by ChEMBL
LigandPNGBDBM50002346(CHEMBL384584 | [D-pro10]Dynorphin A(1-11))
Affinity DataKi:  0.240nMAssay Description:Affinity against Opioid receptor mu 1 was determined by measuring the inhibition of [3H]-DAMGO binding to rat forebrain membranesMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50247749(CHEMBL510583 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)
Affinity DataKi:  0.400nMAssay Description:Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208769(2-[2-(hydroxymethyl)piperazin-1-yl]-6-nitroquinoli...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208770(2-[2-(ethoxymethyl)piperazin-1-yl]-6-nitroquinolin...)
Affinity DataKi:  0.430nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM519((2S)-N-[(2S,3R)-4-[(3S,4aS,8aS)-3-(tert-butylcarba...)
Affinity DataKi:  0.452nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571793((3-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)...)
Affinity DataKi:  0.520nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM9294((3S,4aS,8aS)-N-tert-butyl-2-[(2R,3S)-2-hydroxy-3-[...)
Affinity DataKi:  0.550nMAssay Description:Inhibitory activity against P2 site in HIV protease.More data for this Ligand-Target Pair
In DepthDetails Article
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571830(3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.550nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571802(4-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)t...)
Affinity DataKi:  0.570nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571797((3-((5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)...)
Affinity DataKi:  0.570nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571815(4-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.570nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571817(3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.570nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571814(3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.590nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571772(1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)th...)
Affinity DataKi:  0.600nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM20286(5-I-RTX | 5-iodoresiniferatoxin | [(1R,2R,6R,10S,1...)
Affinity DataKi:  0.610nM ΔG°:  -54.7kJ/mole EC50:  12.2nMpH: 7.4 T: 2°CAssay Description:Binding assay mixtures were set up and contained [3H] RTX, various concentrations of competing ligands, and rVR1-transfected CHO cells. Nonspecific b...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571760(3-((5-((4-carbamimidoyl-2-fluorophenoxy)carbonyl)t...)
Affinity DataKi:  0.680nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetSodium-dependent serotonin transporter(Rattus norvegicus (rat))
Inha University

Curated by ChEMBL
LigandPNGBDBM50208771(2-[(2-methoxymethyl)piperazin-1-yl]-6-nitroquinoli...)
Affinity DataKi:  0.680nMAssay Description:Displacement of [3H]citalopram from Sprague-Dawley rat SERTMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290520(((R)-1-{(S)-1-[(2R,3S)-3-(2-tert-Butylsulfamoyl-et...)
Affinity DataKi:  0.700nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571843(3-((6-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)b...)
Affinity DataKi:  0.700nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50290527(CHEMBL86971 | [(R)-1-((S)-1-{(2R,3S)-3-[2-(Ethyl-i...)
Affinity DataKi:  0.800nMAssay Description:Compound was tested for its inhibitory activity against HIV-1 proteaseMore data for this Ligand-Target Pair
In DepthDetails Article
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50247742(CHEMBL509154 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)
Affinity DataKi:  0.840nMAssay Description:Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571841(3-((6-((4-Carbamimidoylphenoxy)carbonyl)benzo[d]th...)
Affinity DataKi:  0.890nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50247748(CHEMBL510228 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)
Affinity DataKi:  0.890nMAssay Description:Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571766(4-Carbamimidoyl-2-fluorophenyl 2-(4-(methoxycarbon...)
Affinity DataKi:  0.920nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetTransient receptor potential cation channel subfamily V member 1(Rattus norvegicus (rat))
Seoul National University

Curated by ChEMBL
LigandPNGBDBM50247751(CHEMBL449201 | [(1R,2R,6R,10S,11R,15S,17R)-13-benz...)
Affinity DataKi:  0.980nMAssay Description:Displacement of [3H]RTX form rat TRPV1 receptor expressed in CHO/VR1 cell systemMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetEnteropeptidase(Homo sapiens (Human))
LG CHEM, LTD.

US Patent
LigandPNGBDBM571783((1-(5-((4-Carbamimidoyl-2-fluorophenoxy)carbonyl)t...)
Affinity DataKi:  1nMAssay Description:The inhibitory activity of the enteropeptidase inhibitor synthesized using the purified Recombinant Human Enteropeptidase and the substrate Acetyl-As...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM50288947(CHEMBL158033 | N*1*-((S)-1-{(2R,3S)-3-[(1-Isopropy...)
Affinity DataKi:  1nMAssay Description:Inhibitory activity against HIV protease was determinedMore data for this Ligand-Target Pair
In DepthDetails Article
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
TBA

Curated by ChEMBL
LigandPNGBDBM197((2S)-N-[(2S,3R,4R,5S)-3,4-dihydroxy-5-[(2S)-3-meth...)
Affinity DataKi: <1nMAssay Description:Compound was tested for the inhibition activity against HIV-1 proteaseMore data for this Ligand-Target Pair
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