Compile Data Set for Download or QSAR
Report error Found 145 with Last Name = 'chu' and Initial = 'ck'
LigandPNGBDBM17451(5-(4-methylphenyl)-1H-pyrazole | pyrazole analogue...)
Affinity DatapH: 7.5 T: 2°CAssay Description:MetAP2 activity was monitored by measuring the initial velocity of turnover of the artificial substrate Met-AMC. Assays were performed in 96-well mi...More data for this Ligand-Target Pair
In Depth
Date in BDB:
8/30/2007
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50130673(4-Amino-5-fluoro-1-((2R,5R)-4-fluoro-5-hydroxymeth...)
Affinity DataEC50:  3.00E+4nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50130672((+)-1-(4-Fluoro-5-hydroxymethyl-2,5-dihydro-furan-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50130692((+)-4-Amino-1-(4-fluoro-5-hydroxymethyl-2,5-dihydr...)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50130671((+)-1-(4-Fluoro-5-hydroxymethyl-2,5-dihydro-furan-...)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50130675((+)-4-Amino-1-(4-fluoro-5-hydroxymethyl-2,5-dihydr...)
Affinity DataEC50:  89nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50130685((-)-4-Amino-5-fluoro-1-(4-fluoro-5-hydroxymethyl-2...)
Affinity DataEC50:  18nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409711(CHEMBL449667)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409712(CHEMBL473692)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409713(CHEMBL473065)
Affinity DataEC50:  1.15E+4nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409714(CHEMBL473691)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409715(CHEMBL473685)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409716(CHEMBL525052)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409717(CHEMBL2112120)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409718(CHEMBL2112118)
Affinity DataEC50:  8.80E+3nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409719(CHEMBL514452)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409720(CHEMBL515130)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409721(CHEMBL473066)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409722(CHEMBL453416)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409723(CHEMBL475089)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50409724(CHEMBL2112119)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50422482(CHEMBL474033)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50422483(CHEMBL472672)
Affinity DataEC50:  3.85E+4nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50422484(CHEMBL2311165)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50422485(CHEMBL2112548)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50422486(CHEMBL515101)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50422487(CHEMBL475712)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetGag-Pol polyprotein [489-587](Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50422488(CHEMBL472673)
Affinity DataEC50: >1.00E+5nMAssay Description:Anti-HIV-1 activity determined in human peripheral blood mononuclear PBM cells, expressed as EC50More data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138403([(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-2,5-d...)
Affinity DataKd:  1.80E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138406([(2R,5S)-5-(4-amino-2-oxopyrimidin-1(2H)-yl)-1,3-o...)
Affinity DataKd:  1.50E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138405([(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-...)
Affinity DataKd:  1.20E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMedPDB3D3D Structure (crystal)
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138404([(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-...)
Affinity DataKd:  6.40E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50138402([(2R,5S)-5-(4-amino-5-fluoro-2-oxopyrimidin-1(2H)-...)
Affinity DataKd:  3.10E+4nMAssay Description:Equilibrium binding constant at the active site of HIV-1 reverse transcriptaseMore data for this Ligand-Target Pair
In Depth
Date in BDB:
11/10/2009
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50013111(2',3'-didehydro-3'-deoxythymidine | 1-(5-Hydroxyme...)
Affinity DataEC50:  500nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase M184V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50366816(Epzicom | Ziagen | ABACAVIR)
Affinity DataEC50:  5.30E+3nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase wild typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50366817(Epivir)
Affinity DataEC50:  42nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase wild typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50421604(ACH-126443 | ELVUCITABINE)
Affinity DataEC50:  180nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase wild typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50421604(ACH-126443 | ELVUCITABINE)
Affinity DataEC50:  140nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase M184V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50366817(Epivir)
Affinity DataEC50: >5.00E+4nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase M184V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50366816(Epzicom | Ziagen | ABACAVIR)
Affinity DataEC50:  1.55E+4nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase M184V mutantMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase/RNaseH(Human immunodeficiency virus type 1)
The University of Georgia

Curated by ChEMBL
LigandPNGBDBM50013111(2',3'-didehydro-3'-deoxythymidine | 1-(5-Hydroxyme...)
Affinity DataEC50:  450nMAssay Description:In vitro antiviral activity against HIV-1 Reverse transcriptase wild typeMore data for this Ligand-Target Pair
In Depth
Date in BDB:
10/7/2012
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50: 80nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase wild type LAI by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50478156(CHEMBL258936)
Affinity DataIC50: 100nMAssay Description:Inhibition of HIV1 pNL4-3 reverse transcriptase wild type pNL4-3 by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50478156(CHEMBL258936)
Affinity DataIC50: 110nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase wild type LAI by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50: 130nMAssay Description:Inhibition of HIV1 pNL4-3 reverse transcriptase wild type pNL4-3 by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50478159(CHEMBL261773)
Affinity DataIC50: 180nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase wild type LAI by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50478156(CHEMBL258936)
Affinity DataIC50: 190nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase wild type in presence of 5 mM ATP by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50478159(CHEMBL261773)
Affinity DataIC50: 200nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase wild type in presence of 5 mM ATP by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50370476(Combivir | ZIDOVUDINE TRIPHOSPHATE)
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 LAI reverse transcriptase wild type in presence of 5 mM ATP by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
TargetReverse transcriptase(Human immunodeficiency virus type 1)
Emory University

Curated by ChEMBL
LigandPNGBDBM50478156(CHEMBL258936)
Affinity DataIC50: 300nMAssay Description:Inhibition of HIV1 pNL4-3 reverse transcriptase wild type pNL4-3 in presence of 5 mM ATP by heteropolymeric DNA polymerase assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/25/2020
Entry Details Article
PubMed
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