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TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50161093(CHEMBL2112075 | CHEMBL180672 | (R)-2-chloro-6-(2-h...)
Affinity DataIC50: 43nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166511(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 95nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166504(5-Ethyl-3-[2-(2-fluoro-phenyl)-ethyl]-2-(2-hydroxy...)
Affinity DataIC50: 97nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166510(5-Ethyl-2-(2-hydroxy-phenyl)-6-methyl-3-phenethyl-...)
Affinity DataIC50: 100nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166517(5-Cyclopropyl-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-h...)
Affinity DataIC50: 120nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166507(2-(2-Hydroxy-phenyl)-3-phenethyl-4a,5,6,7,8,8a-hex...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166503(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 140nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166505(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 160nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166512(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 170nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162536(6-Fluoro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydrox...)
Affinity DataIC50: 190nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166509(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166514(2-(2-Hydroxy-phenyl)-5,6-dimethyl-3-phenethyl-3H-p...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166508(2-(2-Hydroxy-phenyl)-3-phenethyl-3,4a,5,6,7,7a-hex...)
Affinity DataIC50: 200nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162537(6-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...)
Affinity DataIC50: 210nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162547(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 250nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162538(2-(2-Hydroxy-phenyl)-5-methyl-3-phenethyl-3H-quina...)
Affinity DataIC50: 250nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162554(2-(2-hydroxyphenyl)-3-phenethylquinazolin-4(3H)-on...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162553(6-Chloro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...)
Affinity DataIC50: 300nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162539(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 520nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162552(7-Fluoro-2-(2-hydroxy-phenyl)-3-phenethyl-3H-quina...)
Affinity DataIC50: 600nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162545(2-(2-Hydroxy-phenyl)-8-methyl-3-phenethyl-3H-quina...)
Affinity DataIC50: 700nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162555(3-[2-(3-Chloro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166516(2-(2-Hydroxy-phenyl)-5-methyl-3-phenethyl-6-triflu...)
Affinity DataIC50: 800nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166506(3-[2-(3-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166515(3-[2-(2-Fluoro-phenyl)-ethyl]-2-(2-hydroxy-phenyl)...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162549(7-Chloro-3-[2-(3-fluoro-phenyl)-ethyl]-2-(2-hydrox...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162546(2-(2,5-Dihydroxy-phenyl)-3-phenethyl-3H-quinazolin...)
Affinity DataIC50: 1.60E+3nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50166513(2-(2-Hydroxy-phenyl)-6-methyl-3-phenethyl-3H-pyrim...)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162535(2-(3-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50: 2.80E+3nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162542(2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one | CHE...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration was evaluated for in vitro calcilytic activity against human calcium receptorMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162542(2-Furan-2-yl-3-phenethyl-3H-quinazolin-4-one | CHE...)
Affinity DataIC50: 3.50E+3nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162540(3-Phenethyl-2-phenyl-3H-quinazolin-4-one | CHEMBL1...)
Affinity DataIC50: 1.40E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162541(2-(4-Hydroxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162550(2-(3-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162551(2-(2-Fluoro-phenyl)-3-phenethyl-3H-quinazolin-4-on...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162548(2-(4-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162543(2-(3-Fluoro-phenyl)-3-phenethyl-3H-quinazolin-4-on...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetExtracellular calcium-sensing receptor(Human)
Nps Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50162544(2-(2-Methoxy-phenyl)-3-phenethyl-3H-quinazolin-4-o...)
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibitory concentration against human calcium receptor expressed in HEK 293 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed