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TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50322229(4-(4-Iodophenyl)-1-((4-methoxy-1H-indol-3-yl)methy...)
Affinity DataKi:  0.900nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  1.40nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM21398(4-[4-(4-Chloro-phenyl)-4-hydroxy-piperidin-1-yl]-1...)
Affinity DataKi:  2nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  7.5nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003068(CHEMBL3234537)
Affinity DataKi:  23nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50050467(1-((1H-indol-3-yl)methyl)-4-(4-chlorophenyl)piperi...)
Affinity DataKi:  49nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50322229(4-(4-Iodophenyl)-1-((4-methoxy-1H-indol-3-yl)methy...)
Affinity DataKi:  88nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003066(CHEMBL3234536)
Affinity DataKi:  90nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003074(CHEMBL3234544)
Affinity DataKi:  100nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003068(CHEMBL3234537)
Affinity DataKi:  130nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003063(CHEMBL3234237)
Affinity DataKi:  158nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003065(CHEMBL3234522)
Affinity DataKi:  190nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003073(CHEMBL3234543)
Affinity DataKi:  210nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003066(CHEMBL3234536)
Affinity DataKi:  230nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003071(CHEMBL3234541)
Affinity DataKi:  240nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003070(CHEMBL3234539)
Affinity DataKi:  290nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003064(CHEMBL1503220)
Affinity DataKi:  300nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003072(CHEMBL3234542)
Affinity DataKi:  310nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003073(CHEMBL3234543)
Affinity DataKi:  350nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003071(CHEMBL3234541)
Affinity DataKi:  370nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003069(CHEMBL3234538)
Affinity DataKi:  530nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003069(CHEMBL3234538)
Affinity DataKi:  880nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003063(CHEMBL3234237)
Affinity DataKi:  1.16E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003064(CHEMBL1503220)
Affinity DataKi:  1.90E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003070(CHEMBL3234539)
Affinity DataKi:  3.40E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003074(CHEMBL3234544)
Affinity DataKi:  4.10E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081422(2-((R)-3-{(R)-3-[(S)-2-((S)-Benzyloxycarbonylamino...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081422(2-((R)-3-{(R)-3-[(S)-2-((S)-Benzyloxycarbonylamino...)
Affinity DataKi:  5.00E+3nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003065(CHEMBL3234522)
Affinity DataKi:  9.20E+3nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003072(CHEMBL3234542)
Affinity DataKi:  2.10E+4nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003075(CHEMBL3234545)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]methylspiperone from human D3 receptor expressed in HEK293 cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
National Center For Advancing Translational Sciences

Curated by ChEMBL
LigandPNGBDBM50003075(CHEMBL3234545)
Affinity DataKi: >5.00E+4nMAssay Description:Displacement of [3H]methylspiperone from human D2L receptor expressed in HEK cell membrane after 90 mins by scintillation counting analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081425(2-((R)-3-{(R)-3-[(S)-2-Benzyloxycarbonylamino-3-(1...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081425(2-((R)-3-{(R)-3-[(S)-2-Benzyloxycarbonylamino-3-(1...)
Affinity DataKi:  1.50E+5nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Papaya)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081425(2-((R)-3-{(R)-3-[(S)-2-Benzyloxycarbonylamino-3-(1...)
Affinity DataKi:  2.50E+5nMAssay Description:Inhibitory activity of the compound against papainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Papaya)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081422(2-((R)-3-{(R)-3-[(S)-2-((S)-Benzyloxycarbonylamino...)
Affinity DataKi:  3.80E+5nMAssay Description:Inhibitory activity of the compound against papainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081424(2-((R)-3-{(R)-3-[(S)-2-((S)-Benzyloxycarbonylamino...)
Affinity DataKi:  4.20E+5nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Papaya)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081424(2-((R)-3-{(R)-3-[(S)-2-((S)-Benzyloxycarbonylamino...)
Affinity DataKi:  4.90E+5nMAssay Description:Inhibitory activity of the compound against papainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPapain(Papaya)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081423(2-{(R)-3-[(R)-3-((S)-2-Benzyloxycarbonylamino-3-ph...)
Affinity DataKi:  8.70E+5nMAssay Description:Inhibitory activity of the compound against papainMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin B(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081423(2-{(R)-3-[(R)-3-((S)-2-Benzyloxycarbonylamino-3-ph...)
Affinity DataKi:  1.10E+6nMAssay Description:Inhibitory activity of the compound against Cathepsin BMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPlasminogen(Human)
Brown University

Curated by ChEMBL
LigandPNGBDBM50081423(2-{(R)-3-[(R)-3-((S)-2-Benzyloxycarbonylamino-3-ph...)
Affinity DataKi:  3.00E+6nMAssay Description:Inhibitory activity of the compound against plasminMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549175(CHEMBL4796389)
Affinity DataEC50:  95nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549176(CHEMBL4740312)
Affinity DataEC50:  82nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549177(CHEMBL4759814)
Affinity DataEC50:  94nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549178(CHEMBL4796761)
Affinity DataEC50:  95nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549179(CHEMBL4787728)
Affinity DataEC50:  74nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549180(CHEMBL4740497)
Affinity DataEC50:  168nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549181(CHEMBL4754761)
Affinity DataEC50:  49nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549182(CHEMBL4755709)
Affinity DataEC50:  28nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetD(1B) dopamine receptor(Human)
National Institutes of Health

Curated by ChEMBL
LigandPNGBDBM50549183(CHEMBL4754602)
Affinity DataEC50:  25nMAssay Description:Positive allosteric modulator activity at human dopamine D5 receptor expressed in CHO-K1 cells assessed as potentiation of dopamine-induced beta-arre...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
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