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TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482293(US10919843, Compound II)
Affinity DataEC50:  4.30E+3nMAssay Description:NIH3T3-EPO-luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482294(US10919843, Compound III)
Affinity DataEC50:  3.60E+3nMAssay Description:NIH3T3-EPO-luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482295(US10919843, Compound IV)
Affinity DataEC50:  3.20E+3nMAssay Description:NIH3T3-EPO-luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482296(US10919843, Compound V)
Affinity DataEC50:  1.80E+3nMAssay Description:NIH3T3-EPO-luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482297(US10919843, Compound VI)
Affinity DataEC50:  2.80E+3nMAssay Description:NIH3T3-EPO-luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482298(US10919843, Compound VII)
Affinity DataEC50:  2.90E+3nMAssay Description:NIH3T3-EPO-luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482299(US10919843, Compound VIII)
Affinity DataEC50:  2.60E+3nMAssay Description:NIH3T3-EPO-luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482300(US10919843, Compound IX)
Affinity DataEC50:  2.50E+3nMAssay Description:NIH3T3-EPO-luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482301(US10919843, Compound X)
Affinity DataEC50:  3.30E+3nMAssay Description:NIH3T3-EPO-luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482293(US10919843, Compound II)
Affinity DataEC50:  3.20E+3nMAssay Description:HaCaT-EPO-Luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482294(US10919843, Compound III)
Affinity DataEC50:  1.70E+3nMAssay Description:HaCaT-EPO-Luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482295(US10919843, Compound IV)
Affinity DataEC50:  1.60E+3nMAssay Description:HaCaT-EPO-Luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482296(US10919843, Compound V)
Affinity DataEC50:  1.90E+3nMAssay Description:HaCaT-EPO-Luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482297(US10919843, Compound VI)
Affinity DataEC50:  4.00E+3nMAssay Description:HaCaT-EPO-Luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482298(US10919843, Compound VII)
Affinity DataEC50:  5.50E+3nMAssay Description:HaCaT-EPO-Luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482299(US10919843, Compound VIII)
Affinity DataEC50:  1.40E+3nMAssay Description:HaCaT-EPO-Luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482300(US10919843, Compound IX)
Affinity DataEC50:  1.40E+3nMAssay Description:HaCaT-EPO-Luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetHypoxia-inducible factor 1-alpha(Human)
Emerald Health Pharmaceuticals

US Patent
LigandPNGBDBM482301(US10919843, Compound X)
Affinity DataEC50:  1.20E+3nMAssay Description:HaCaT-EPO-Luc cells were maintained at 37° C. in a humidified atmosphere containing 5% CO2 in DMEM supplemented with 10% fetal calf serum (FBS), and ...More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/2/2021
Entry Details
Go to US Patent

TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456756(CHEMBL4214981)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456758(CHEMBL1631518)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456759(CHEMBL4215902)
Affinity DataEC50:  1.15E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456757(CHEMBL4209008)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456760(CHEMBL4205263)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456761(CHEMBL4213753)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456762(CHEMBL4215072)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456763(CHEMBL4210989)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456765(CHEMBL1915188)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456766(CHEMBL4209967)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456764(CHEMBL4218752)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456769(CHEMBL4211797)
Affinity DataEC50:  1.10E+3nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM217379(CDDO-Me, 2)
Affinity DataEC50:  60nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456770(CHEMBL4208824)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456767(CHEMBL4211445)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456755(CHEMBL4212101)
Affinity DataEC50: >2.50E+4nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear factor erythroid 2-related factor 2(Human)
University of Eastern Piedmont

Curated by ChEMBL
LigandPNGBDBM50456768(CHEMBL4211885)
Affinity DataEC50:  2.45E+3nMAssay Description:Activation of Nrf2 (unknown origin) expressed in human HaCaT-ARE-luc cells after 6 hrs by luciferase reporter gene assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetNuclear receptor subfamily 1 group I member 2(Human)
Merck Research Laboratories Boston

Curated by ChEMBL
LigandPNGBDBM50498590(CHEMBL3609637)
Affinity DataEC50: >3.00E+4nMAssay Description:Activation of PXR (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50529621(CHEMBL4563191)
Affinity DataEC50:  7.10E+3nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529622(CHEMBL4562991)
Affinity DataEC50:  1.14E+4nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529623(CHEMBL4460360)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529624(CHEMBL4473530)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529625(CHEMBL4436329)
Affinity DataEC50:  8.90E+3nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529622(CHEMBL4562991)
Affinity DataEC50:  1.14E+4nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529621(CHEMBL4563191)
Affinity DataEC50:  7.10E+3nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50233538(3beta-hydroxy-11-oxoolean-12-en-30-oic acid | glyc...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50329195((2S,4aS,6aS,6bR,8aR,10S,12aS,12bR,14bR)-N,10-dihyd...)
Affinity DataEC50: >5.00E+4nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529626(CHEMBL4463388)
Affinity DataEC50:  2.40E+3nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529627(CHEMBL4464252)
Affinity DataEC50:  2.60E+3nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529628(CHEMBL4583726)
Affinity DataEC50:  6.80E+3nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529629(CHEMBL4472548)
Affinity DataEC50:  5.80E+3nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
LigandPNGBDBM50529630(CHEMBL4589866)
Affinity DataEC50:  5.00E+3nMAssay Description:Inhibition of PHD (unknown origin) expressed in mouse NIH/3T3 cells harboring HRE-driven luciferase gene assessed as transactivation of HIF1alpha aft...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/26/2021
Entry Details Article
PubMed
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