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TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50024101((S)-2-((S)-2-Mercaptomethyl-3-phenyl-propionylamin...)
Affinity DataKi:  0.700nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50024102(((S)-2-Mercaptomethyl-3-phenyl-propionylamino)-ace...)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023103(CHEMBL3298934)
Affinity DataKi:  1.5nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023104(CHEMBL3298935)
Affinity DataKi:  2nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023097(CHEMBL3298860)
Affinity DataKi:  2.5nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023069(CHEMBL3298859)
Affinity DataKi:  2.90nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023131(CHEMBL3298940)
Affinity DataKi:  3.5nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023128(CHEMBL3298937)
Affinity DataKi:  8.20nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023134(CHEMBL3298943)
Affinity DataKi:  11nMAssay Description:Inhibition of human recombinant APN using L-Ala-beta-NA as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023133(CHEMBL3298942)
Affinity DataKi:  11nMAssay Description:Inhibition of human recombinant APN using L-Ala-beta-NA as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023135(CHEMBL3298944)
Affinity DataKi:  13nMAssay Description:Inhibition of human recombinant APN using L-Ala-beta-NA as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023132(CHEMBL3298941)
Affinity DataKi:  18nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023127(CHEMBL3298936)
Affinity DataKi:  24nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023136(CHEMBL3298945)
Affinity DataKi:  35nMAssay Description:Inhibition of human recombinant APN using L-Ala-beta-NA as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023129(CHEMBL3298938)
Affinity DataKi:  44nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023137(CHEMBL3298946)
Affinity DataKi:  47nMAssay Description:Inhibition of human recombinant APN using L-Ala-beta-NA as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetAminopeptidase N(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023152(CHEMBL3298947)
Affinity DataKi:  55nMAssay Description:Inhibition of human recombinant APN using L-Ala-beta-NA as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNeprilysin(Homo sapiens (Human))
Pharmaleads

Curated by ChEMBL
LigandPNGBDBM50023130(CHEMBL3298939)
Affinity DataKi:  59nMAssay Description:Inhibition of human recombinant NEP using Suc-Ala-Ala-Phe-AMC as substrate after 30 mins by fluorimetryMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed