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TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM576619(US11472787, Compound CP 55 940)
Affinity DataEC50:  0.900nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM576619(US11472787, Compound CP 55 940)
Affinity DataEC50:  1.73nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288368(CHEMBL4161934 | US11472787, Compound 10,11-EDP-EA)
Affinity DataEC50:  0.430nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288368(CHEMBL4161934 | US11472787, Compound 10,11-EDP-EA)
Affinity DataEC50:  22.5nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288371(CHEMBL4177060 | US11472787, Compound 10,11-EDP-IA)
Affinity DataEC50:  0.0700nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288371(CHEMBL4177060 | US11472787, Compound 10,11-EDP-IA)
Affinity DataEC50:  0.0800nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288369(CHEMBL4172580 | US11472787, Compound 10,11-EDP-NA)
Affinity DataEC50:  0.190nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288369(CHEMBL4172580 | US11472787, Compound 10,11-EDP-NA)
Affinity DataEC50:  7.30nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288370(CHEMBL4169198 | US11472787, Compound 10,11-EDP-CA)
Affinity DataEC50:  0.0300nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288370(CHEMBL4169198 | US11472787, Compound 10,11-EDP-CA)
Affinity DataEC50:  0.460nMAssay Description:Binding of the parent compounds to putative receptors CNR1 and CNR2 (cannabinoid receptors 1& 2) was measured by a Presto-Tango assay (FIG. 5A and FI...More data for this Ligand-Target Pair
In DepthDetails
US Patent

TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288368(CHEMBL4161934 | US11472787, Compound 10,11-EDP-EA)
Affinity DataEC50:  23nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB2 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  1.70nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB2 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288368(CHEMBL4161934 | US11472787, Compound 10,11-EDP-EA)
Affinity DataEC50:  0.430nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB1 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288369(CHEMBL4172580 | US11472787, Compound 10,11-EDP-NA)
Affinity DataEC50:  0.190nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB1 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288370(CHEMBL4169198 | US11472787, Compound 10,11-EDP-CA)
Affinity DataEC50:  0.0300nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB1 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288369(CHEMBL4172580 | US11472787, Compound 10,11-EDP-NA)
Affinity DataEC50:  7.30nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB2 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288370(CHEMBL4169198 | US11472787, Compound 10,11-EDP-CA)
Affinity DataEC50:  0.460nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB2 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50072775(ChEMBL_75020 | 5-(1,1-Dimethyl-heptyl)-2-[(1R,2R,5...)
Affinity DataEC50:  0.900nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB1 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetCannabinoid receptor 2(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288371(CHEMBL4177060 | US11472787, Compound 10,11-EDP-IA)
Affinity DataEC50:  0.0800nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB2 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCannabinoid receptor 1(Human)
The Board of Trustees of The University of Illinois

US Patent
LigandPNGBDBM50288371(CHEMBL4177060 | US11472787, Compound 10,11-EDP-IA)
Affinity DataEC50:  0.0700nMAssay Description:Agonist activity at N-terminal FLAG-tagged human CB1 receptor transfected in human HTLA cells assessed as induction of beta-arrestin-recruitment afte...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataKd:  360nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617720(CHEMBL5407395)
Affinity DataKd:  17nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617725(CHEMBL5404686)
Affinity DataKd:  4.5nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617728(CHEMBL5415149)
Affinity DataKd:  0.5nMAssay Description:Binding affinity to autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation ana...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50177716(CHEMBL3813873 | US11679110, Compound Pexidartinib ...)
Affinity DataKd:  5.80nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
In DepthDetails
PubMedPDB3D3D Structure (crystal)
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617720(CHEMBL5407395)
Affinity DataKd:  220nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617725(CHEMBL5404686)
Affinity DataKd:  80nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetMacrophage colony-stimulating factor 1 receptor(Human)
Norwegian University of Science and Technology (Ntnu

Curated by ChEMBL
LigandPNGBDBM50617728(CHEMBL5415149)
Affinity DataKd:  36nMAssay Description:Binding affinity to non-autoinhibited form of CSF1R (unknown origin) assessed as dissociation constant incubated for 1 hr by qPCR based Hill equation...More data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetProgrammed cell death 1 ligand 1(Human)
Zhejiang University

Curated by ChEMBL
LigandPNGBDBM50627655(CHEMBL5398715)
Affinity DataKd: <1.00E+3nMAssay Description:Binding affinity to human PD-L1 expressed in Escherichia coli strain BL21 assessed as dissociation constant by NMR spectroscopic analysisMore data for this Ligand-Target Pair
In DepthDetails
PubMed
TargetP2Y purinoceptor 2(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209659(uridine 5'-[3-alpha-D-glucopyranosyl dihydrogen di...)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at human P2Y2 receptor expressed in human 1321N1 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50197974(udp-N-acetyl-glucosamine)
Affinity DataEC50:  4.38E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209659(uridine 5'-[3-alpha-D-glucopyranosyl dihydrogen di...)
Affinity DataEC50:  261nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209669(MRS-2670 | diphosphoric acid 1-alpha-D-glucopyrano...)
Affinity DataEC50:  49nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209663(MRS-2670 | diphosphoric acid 1-alpha-D-glucopyrano...)
Affinity DataEC50:  290nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304030(Diphosphoric Acid 1''-beta-D-[1'']Glucopyranosyl E...)
Affinity DataEC50:  588nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209666(URIDINE-5'-DIPHOSPHATE-MANNOSE | CHEMBL227711)
Affinity DataEC50:  910nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209668(Galactose-Uridine-5'-Diphosphate | CHEMBL439009)
Affinity DataEC50:  670nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304031(Diphosphoric Acid 1''-alpha-D-[1'']Fucopyranosyl E...)
Affinity DataEC50:  562nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304032(URIDINE-5'-DIPHOSPHATE-2-DEOXY-2-FLUORO-ALPHA-D-GL...)
Affinity DataEC50:  2.50E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304033(Diphosphoric Acid 1''-alpha-D-[1''](3''-Fluoro-3''...)
Affinity DataEC50:  361nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304034(URIDINE-5'-DIPHOSPHATE-4-DEOXY-4-FLUORO-ALPHA-D-GA...)
Affinity DataEC50:  567nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304035(Diphosphoric Acid 1''-alpha-D-[1''](6''-Fluoro-6''...)
Affinity DataEC50:  905nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209665(uridine 5'-[3-(alpha-D-glucopyranuronosyl) dihydro...)
Affinity DataEC50:  370nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304036(Diphosphoric acid 1''-alpha-D-[1''](glucuronic aci...)
Affinity DataEC50:  2.59E+3nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304037({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydropyr...)
Affinity DataEC50:  496nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304038(Diphosphoric Acid 1''-alpha-D-[6'']Glucopyranosyl ...)
Affinity DataEC50:  373nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304039(Diphosphoric Acid 1''-alpha-D-[6'']Mannopyranosyl ...)
Affinity DataEC50:  658nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304040(Diphosphoric Acid 1''-alpha-D-[5'']Ribofuranosyl E...)
Affinity DataEC50:  238nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50304041(Diphosphoric Acid 1''-alpha-D-[5'']Arabinofuranosy...)
Affinity DataEC50:  460nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetP2Y purinoceptor 14(Human)
National Institute of Diabetes and Digestive and Kidney Diseases

Curated by ChEMBL
LigandPNGBDBM50209661([({[(2R,3S,4R,5R)-5-(2,4-dioxo-1,2,3,4-tetrahydrop...)
Affinity DataEC50:  880nMAssay Description:Agonist activity at human P2Y14 receptor expressed in human COS7 cellsMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
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