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TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063292(CHEMBL349426 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...)
Affinity DataKi:  0.0200nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063279(CHEMBL309623 | Cyclohexanecarboxylic acid {4-[2-(4...)
Affinity DataKi:  0.140nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063281((4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...)
Affinity DataKi:  0.5nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50455438(CHEMBL3084971)
Affinity DataKi:  1.90nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063280(CHEMBL355371 | {4-[2-(4-Pyridin-2-yl-piperazin-1-y...)
Affinity DataKi:  2.20nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055721(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  2.60nMAssay Description:Binding affinity was determined in vitro on rat striatum using [3H]-N-propylnorapomorphine against Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063281((4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...)
Affinity DataKi:  3nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071235(CHEMBL65078 | Cyclopropylmethyl-[3-(2,4-dichloro-p...)
Affinity DataKi:  3.20nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063292(CHEMBL349426 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...)
Affinity DataKi:  3.20nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063291(CHEMBL78791 | Thiophene-2-carboxylic acid {4-[2-(4...)
Affinity DataKi:  3.40nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063296(CHEMBL165679 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...)
Affinity DataKi:  3.5nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063276(CHEMBL164604 | {4-[2-(4-Phenyl-3,6-dihydro-2H-pyri...)
Affinity DataKi:  3.70nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063276(CHEMBL164604 | {4-[2-(4-Phenyl-3,6-dihydro-2H-pyri...)
Affinity DataKi:  3.90nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063277((4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  4.5nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063286(CHEMBL164723 | {4-[2-(4-Pyridin-3-yl-piperazin-1-y...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063288(CHEMBL165047 | Methyl-{4-[2-(4-phenyl-piperazin-1-...)
Affinity DataKi:  4.70nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063276(CHEMBL164604 | {4-[2-(4-Phenyl-3,6-dihydro-2H-pyri...)
Affinity DataKi:  4.70nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063288(CHEMBL165047 | Methyl-{4-[2-(4-phenyl-piperazin-1-...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071234(Butyl-[3-(2,4-dichloro-phenyl)-2,5-dimethyl-pyrazo...)
Affinity DataKi:  5nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063298((4-{2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-eth...)
Affinity DataKi:  5nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063296(CHEMBL165679 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...)
Affinity DataKi:  5.20nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063295(CHEMBL165664 | [4-(4-Phenyl-piperazin-1-ylmethyl)-...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063283((4-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...)
Affinity DataKi:  6nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063285(CHEMBL165056 | Pyrimidin-2-yl-(4-{2-[4-(3-trifluor...)
Affinity DataKi:  6nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071238(3-(2,4-Dichloro-phenyl)-2,5-dimethyl-7-(2-propyl-p...)
Affinity DataKi:  6.40nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063289(CHEMBL165140 | {4-[3-(4-Phenyl-piperazin-1-yl)-pro...)
Affinity DataKi:  7.40nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063277((4-{2-[4-(4-Fluoro-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataKi:  8.5nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055719(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  8.60nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063294(CHEMBL349980 | Pyrimidin-2-yl-{4-[2-(4-pyrimidin-2...)
Affinity DataKi:  8.60nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055725(3-{4-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-eth...)
Affinity DataKi:  8.70nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063286(CHEMBL164723 | {4-[2-(4-Pyridin-3-yl-piperazin-1-y...)
Affinity DataKi:  9.5nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063297(CHEMBL166252 | Pyrimidin-2-yl-{4-[2-(4-thiazol-2-y...)
Affinity DataKi:  10nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071229(CHEMBL302645 | [3-(2,4-Dichloro-phenyl)-2,5-dimeth...)
Affinity DataKi:  11nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063281((4-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...)
Affinity DataKi:  11nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063298((4-{2-[4-(2,3-Dichloro-phenyl)-piperazin-1-yl]-eth...)
Affinity DataKi:  11nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063280(CHEMBL355371 | {4-[2-(4-Pyridin-2-yl-piperazin-1-y...)
Affinity DataKi:  12nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063283((4-{2-[4-(4-Methoxy-phenyl)-piperazin-1-yl]-ethyl}...)
Affinity DataKi:  13nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063285(CHEMBL165056 | Pyrimidin-2-yl-(4-{2-[4-(3-trifluor...)
Affinity DataKi:  13nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063296(CHEMBL165679 | {4-[2-(4-Phenyl-piperazin-1-yl)-eth...)
Affinity DataKi:  13.7nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50002173(3-(4-(3,6-dihydro-4-phenyl-1(2H)-pyridinyl)butyl)-...)
Affinity DataKi:  14nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCorticotropin-releasing factor receptor 1(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50071233(Butyl-[3-(2-chloro-phenyl)-2,5-dimethyl-pyrazolo[1...)
Affinity DataKi:  15nMAssay Description:Displacement of [125I]-0-CRF from human Corticotropin releasing factor receptor 1 expressed in CHO cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063289(CHEMBL165140 | {4-[3-(4-Phenyl-piperazin-1-yl)-pro...)
Affinity DataKi:  16nMAssay Description:The binding affinity of the compound was determined by measuring its ability to displace [3H]-8-OH-DPAT radioligand in 5-hydroxytryptamine 1A recepto...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063288(CHEMBL165047 | Methyl-{4-[2-(4-phenyl-piperazin-1-...)
Affinity DataKi:  24nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063286(CHEMBL164723 | {4-[2-(4-Pyridin-3-yl-piperazin-1-y...)
Affinity DataKi:  25nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50063280(CHEMBL355371 | {4-[2-(4-Pyridin-2-yl-piperazin-1-y...)
Affinity DataKi:  26nMAssay Description:Binding affinity determined by measuring displacement of [3H]-spiperone from cloned Human Dopamine receptor D3 in CHO-K1 cellsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50455438(CHEMBL3084971)
Affinity DataKi:  28nMAssay Description:Binding affinity determined by measuring its ability to displace [3H]-N-0437 radioligand in CHO-K1 cells on Cloned Human Dopamine receptor D2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055731(3-{4-[2-(4-Phenyl-3,6-dihydro-2H-pyridin-1-yl)-eth...)
Affinity DataKi:  28nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Division of Warner Lambert

Curated by ChEMBL
LigandPNGBDBM50055727(5-Methoxy-3-{4-[2-(4-pyridin-2-yl-piperazin-1-yl)-...)
Affinity DataKi:  29nMAssay Description:In vitro binding affinity for dopamine receptor D2 on rat striatal membranes by [3H]-spiperone displacement.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(3) dopamine receptor(Human)
Warner-Lambert

Curated by ChEMBL
LigandPNGBDBM50055721(3-{4-[2-(4-Pyridin-2-yl-piperazin-1-yl)-ethyl]-cyc...)
Affinity DataKi:  29nMAssay Description:In vitro binding affinity of the compound towards human recombinant Dopamine receptor D3 receptor expressed in CHO-K1 cells was determined using [3H]...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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