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Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056378(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  0.300nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056376(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  0.5nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056368(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataIC50:  0.800nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056384(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  1.20nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056382(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  1.30nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056370(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM10755(14C-5-hydroxy tryptamine creatinine disulfate | 2-...)
Affinity DataIC50:  3nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056369(3-Amino-5,6-dimethyl-2-[3-(4-phenyl-piperazin-1-yl...)
Affinity DataIC50:  3.30nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056362(3-Amino-5,6-dimethyl-2-[3-(4-pyrimidin-2-yl-pipera...)
Affinity DataIC50:  6.80nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056371(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Affinity DataIC50:  7nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056362(3-Amino-5,6-dimethyl-2-[3-(4-pyrimidin-2-yl-pipera...)
Affinity DataIC50:  20nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-BRL-43694 binding to 5-hydroxytryptamine 3 receptor in rat cortical membra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056364(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Affinity DataIC50:  24nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056383(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethyl}-...)
Affinity DataIC50:  42nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056363(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Affinity DataIC50:  46nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056361(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Affinity DataIC50:  59nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056378(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  60nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056379(3,5,6-Trimethyl-2-[3-(4-pyrimidin-2-yl-piperazin-1...)
Affinity DataIC50:  65nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056377(2-{2-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-ethylsu...)
Affinity DataIC50:  97nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056368(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataIC50:  100nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-SCH-23,390 binding to Dopamine receptor D1 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056373(5,6-Dimethyl-2-[3-(4-pyrimidin-2-yl-piperazin-1-yl...)
Affinity DataIC50:  226nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056368(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cortical memb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056378(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  300nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cortical memb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056360(5,6-Dimethyl-2-[3-(4-naphthalen-1-yl-piperazin-1-y...)
Affinity DataIC50:  355nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056365(2-[3-(4-Naphthalen-1-yl-piperazin-1-yl)-propylsulf...)
Affinity DataIC50:  371nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056385(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Affinity DataIC50:  386nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056378(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  400nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-SCH-23,390 binding to Dopamine receptor D1 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056375(2-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propylsu...)
Affinity DataIC50:  460nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056366(2-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyls...)
Affinity DataIC50:  497nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056359(2-[3-(4-Pyrimidin-2-yl-piperazin-1-yl)-propylsulfa...)
Affinity DataIC50:  505nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056367(3-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propyl}...)
Affinity DataIC50:  511nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056368(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-BRL-43694 binding to 5-hydroxytryptamine 3 receptor in rat cortical membra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056362(3-Amino-5,6-dimethyl-2-[3-(4-pyrimidin-2-yl-pipera...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-SCH-23,390 binding to Dopamine receptor D1 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50056378(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  600nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in pig cortical mem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056378(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  700nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-5-HT binding to 5-hydroxytryptamine 1B receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(1A) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056368(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 3A/3B(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056378(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperazin-1-yl]...)
Affinity DataIC50:  800nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-BRL-43694 binding to 5-hydroxytryptamine 3 receptor in rat cortical membra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056380(2-{3-[4-(2-Chloro-phenyl)-piperazin-1-yl]-propylsu...)
Affinity DataIC50:  943nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056372(2-{3-[4-(3-Chloro-phenyl)-piperazin-1-yl]-propylsu...)
Affinity DataIC50:  986nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056362(3-Amino-5,6-dimethyl-2-[3-(4-pyrimidin-2-yl-pipera...)
Affinity DataIC50:  1.00E+3nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-ketanserin binding to 5-hydroxytryptamine 2A receptor in rat cortical memb...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1B(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056368(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataIC50:  1.40E+3nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-5-HT binding to 5-hydroxytryptamine 1B receptor in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056381(4-{3-[4-(2-Methoxy-phenyl)-piperazin-1-yl]-propoxy...)
Affinity DataIC50:  1.42E+3nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50056368(3-Amino-2-{3-[4-(2-methoxy-phenyl)-piperidin-1-yl]...)
Affinity DataIC50:  1.50E+3nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in pig cortical mem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 2C(Human)
Università

Curated by ChEMBL
LigandPNGBDBM50056362(3-Amino-5,6-dimethyl-2-[3-(4-pyrimidin-2-yl-pipera...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-mesulergine binding to 5-hydroxytryptamine 2C receptor in pig cortical mem...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetD(2) dopamine receptor(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056362(3-Amino-5,6-dimethyl-2-[3-(4-pyrimidin-2-yl-pipera...)
Affinity DataIC50:  2.00E+3nMAssay Description:In vitro inhibitory concentration of the compound against radioligand [3H]-spiperone binding to Dopamine receptor D2 in rat striatal membraneMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Target5-hydroxytryptamine receptor 1A(Rat)
Università

Curated by ChEMBL
LigandPNGBDBM50056374(2-[3-(4-Naphthalen-1-yl-piperazin-1-yl)-propylsulf...)
Affinity DataIC50:  2.01E+3nMAssay Description:In vitro inhibitory concentration against radioligand [3H]-8-OH-DPAT binding to 5-hydroxytryptamine 1A receptor in rat hippocampal membrane.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50182752(CHEMBL3818018)
Affinity DataIC50:  3.13E+4nMAssay Description:Inhibition of human Akt1 PH domain using AKTide-2T as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetRAC-alpha serine/threonine-protein kinase(Human)
University of Milano-Bicocca

Curated by ChEMBL
LigandPNGBDBM50431630(KRX-0401 | PERIFOSINE)
Affinity DataIC50:  4.34E+4nMAssay Description:Inhibition of human Akt1 PH domain using AKTide-2T as substrate by ELISAMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed