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TargetSteryl-sulfatase(Rattus norvegicus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  0.0600nMAssay Description:Inhibition of estrone sulfatase in homogeneous rat mammary tumorsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSteryl-sulfatase(Homo sapiens (Human))
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50148911((3beta)-3-hydroxyurs-12-en-28-oic acid | 3beta-hyd...)
Affinity DataIC50:  0.120nMAssay Description:Inhibition of estrone sulfatase in human MCF7 cell microsomesMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEstrogen receptor alpha(Bos taurus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50610464(CHEMBL5284918)
Affinity DataIC50:  60nMAssay Description:Displacement of [3H]-17beta-estradiol from bovine uterine estrogen receptor by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetSulfotransferase 1A1(Rattus norvegicus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSulfotransferase 1A1(Rattus norvegicus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSulfotransferase 1A1(Rattus norvegicus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSulfotransferase 1A1(Rattus norvegicus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM23420(7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3...)
Affinity DataIC50:  290nMAssay Description:Inhibition of rat liver SULT1A1-mediated oestradiol sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetEstrogen receptor alpha(Bos taurus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50610463(CHEBI:67889 | NYASOL)
Affinity DataIC50:  400nMAssay Description:Displacement of [3H]-17beta-estradiol from bovine uterine estrogen receptor by competitive binding assayMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails PubMed
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50544161(CHEMBL4640122)
Affinity DataIC50:  3.50E+3nMAssay Description:Inhibition of PRMT1 (unknown origin) using [3H]-SAM as substrate preincubated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50544164(CHEMBL4632868)
Affinity DataIC50:  1.00E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) using [3H]-SAM as substrate preincubated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50544163(CHEMBL4640252)
Affinity DataIC50:  1.99E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) using [3H]-SAM as substrate preincubated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50544162(CHEMBL4646129)
Affinity DataIC50:  2.38E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) using [3H]-SAM as substrate preincubated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein arginine N-methyltransferase 1(Homo sapiens)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM50544165(CHEMBL4646898)
Affinity DataIC50:  2.90E+4nMAssay Description:Inhibition of PRMT1 (unknown origin) using [3H]-SAM as substrate preincubated for 15 mins followed by substrate addition measured after 1 hrMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSulfotransferase 2A1(Rattus norvegicus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM19459(5,7-dihydroxy-3-(4-hydroxyphenyl)-4H-chromen-4-one...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat SULT2A1-mediated dehydroepiandrosterone sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSulfotransferase 2A1(Rattus norvegicus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM7462(3,5,7-trihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat SULT2A1-mediated dehydroepiandrosterone sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSulfotransferase 2A1(Rattus norvegicus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM23420(7,4′-Dihydroxy-isoflavone (3a) | 7-hydroxy-3...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat SULT2A1-mediated dehydroepiandrosterone sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed
TargetSulfotransferase 2A1(Rattus norvegicus)
Central University of Punjab

Curated by ChEMBL
LigandPNGBDBM7460(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Affinity DataIC50:  3.40E+4nMAssay Description:Inhibition of rat SULT2A1-mediated dehydroepiandrosterone sulfonation incubated for 20 minsMore data for this Ligand-Target Pair
In DepthDetails PubMed