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TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296224(1-(4-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276625(1-Adamantan-1-yl-3-[3-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296223(1-(4-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296214(1-(4-fluoro-3-(3-morpholinopropoxy)phenyl)-3-(4-(t...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296210(1-Adamantan-1-yl-3-[4-fluoro-3-(3-morpholin-4-yl-p...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM25743(1-cycloheptyl-3-(1-acetylpiperidin-4-yl)urea | US8...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276625(1-Adamantan-1-yl-3-[3-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  0.800nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276673(1-(3-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  1nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191898(3-[4-(3-adamantan-1-yl-ureido)-piperidine-1-carbon...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191882(4-[4-(3-adamantan-1-yl-ureido)-piperidine-1-carbon...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191859(1-adamantan-1-yl-3-[1-(2,2,2-trifluoro-acetyl)-pip...)
Affinity DataIC50:  1.10nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276673(1-(3-(3-morpholinopropoxy)phenyl)-3-(4-(trifluorom...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191867(1-adamantan-1-yl-3-[1-(pyridine-2-carbonyl)-piperi...)
Affinity DataIC50:  1.20nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296226(2-Adamantan-1-yl-N-[4-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191865(1-adamantan-1-yl-3-(1-benzoyl-piperidin-4-yl)-urea...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296213(1-(4-fluoro-3-(3-morpholinopropoxy)phenyl)-3-(4-(t...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50223389(1-Adamantan-1-yl-3-[4-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  1.30nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191857(4-{4-[(3-adamantan-1-yl-ureido)-methyl]-piperidine...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296225(1-(4-chlorophenyl)-3-(4-(3-morpholinopropoxy)pheny...)
Affinity DataIC50:  1.5nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335965(1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335964(1-(1-nicotinoylpiperidin-4-yl)-3-(4-(trifluorometh...)
Affinity DataIC50:  1.60nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191880(2-[4-(3-adamantan-1-yl-ureido)-piperidine-1-carbon...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191897(1-adamantan-1-yl-3-[1-(pyridine-3-carbonyl)-piperi...)
Affinity DataIC50:  1.70nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191893(1-adamantan-1-yl-3-[1-(2,2,2-trifluoro-acetyl)-pip...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191870(2-{4-[(3-adamantan-1-yl-ureido)-methyl]-piperidine...)
Affinity DataIC50:  1.80nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335966(1-Adamantan-1-yl-3-(1-methanesulfonyl-piperidin-4-...)
Affinity DataIC50:  1.90nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296197(1-(4-chlorophenyl)-3-(3-(3-morpholinopropoxy)pheny...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191853(1-adamantan-1-yl-3-[1-(pyridine-4-carbonyl)-piperi...)
Affinity DataIC50:  2.10nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276676(2-Adamantan-1-yl-N-[3-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276676(2-Adamantan-1-yl-N-[3-(3-morpholin-4-yl-propoxy)-p...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296219(1-Adamantan-1-yl-3-[3-(3-morpholin-4-yl-propoxy)-c...)
Affinity DataIC50:  2.5nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191862(1-adamantan-1-yl-3-(1-butyryl-piperidin-4-yl)-urea...)
Affinity DataIC50:  2.60nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191858(5-[4-(3-adamantan-1-yl-ureido)-piperidin-1-yl]-5-o...)
Affinity DataIC50:  2.70nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335967(1-(1-(isopropylsulfonyl)piperidin-4-yl)-3-(4-(trif...)
Affinity DataIC50:  2.90nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM25737(12-[(adamantan-1-ylcarbamoyl)amino]dodecanoic acid...)
Affinity DataIC50:  3nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Mus musculus (Mouse))
Ar£Te Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191854(CHEMBL436774 | N-(1-acetyl-piperidin-4-yl)-N'-(ada...)
Affinity DataIC50:  3nMAssay Description:Inhibition of mouse soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191881(1-adamantan-1-yl-3-(1-benzoyl-piperidin-4-ylmethyl...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191887(1-adamantan-1-yl-3-(1-propionyl-piperidin-4-yl)-ur...)
Affinity DataIC50:  3.20nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191895(4-[4-(3-adamantan-1-yl-ureido)-piperidine-1-carbon...)
Affinity DataIC50:  3.30nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191892(5-{4-[(3-adamantan-1-yl-ureido)-methyl]-piperidin-...)
Affinity DataIC50:  3.40nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335968(1-(1-(methylsulfonyl)piperidin-4-yl)-3-(4-(trifluo...)
Affinity DataIC50:  3.70nMAssay Description:Inhibition of human soluble epoxide hydrolaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276626(1-cyclohexyl-3-(3-(3-morpholinopropoxy)phenyl)urea...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of soluble epoxide hydrolase (unknown origin) by fluorescence assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50276626(1-cyclohexyl-3-(3-(3-morpholinopropoxy)phenyl)urea...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50335966(1-Adamantan-1-yl-3-(1-methanesulfonyl-piperidin-4-...)
Affinity DataIC50:  3.90nMAssay Description:Inhibition of soluble epoxide hydrolase in HUVEC assessed inhibition of as conversion of 14, 15-EET to 14, 15-DHETMore data for this Ligand-Target Pair
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191861(3-{4-[(3-adamantan-1-yl-ureido)-methyl]-piperidine...)
Affinity DataIC50:  4.10nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296215(1-(4-chlorophenyl)-3-(4-fluoro-3-(3-morpholinoprop...)
Affinity DataIC50:  4.80nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191878(1-(1-Acetyl-piperidin-4-ylmethyl)-3-adamantan-1-yl...)
Affinity DataIC50:  5nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296220(2-Adamantan-1-yl-N-[3-(3-morpholin-4-yl-propoxy)-c...)
Affinity DataIC50:  5.20nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50191864(1-adamantan-1-yl-3-[1-(pyridine-3-carbonyl)-piperi...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of soluble epoxide hydroxylase by kinetic fluorescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetBifunctional epoxide hydrolase 2(Homo sapiens (Human))
Arete Therapeutics

Curated by ChEMBL
LigandPNGBDBM50296221(1-cyclohexyl-3-(4-(3-morpholinopropoxy)phenyl)urea...)
Affinity DataIC50:  5.40nMAssay Description:Inhibition of human soluble epoxide hydrolase by fluorescent endpoint assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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