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TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239931(CHEMBL4067995 | US10287286, Example 142)
Affinity DataIC50:  8nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239883(CHEMBL4090769 | US10287286, Example 5)
Affinity DataIC50:  10nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239889(CHEMBL4072842 | US10287286, Example 100)
Affinity DataIC50:  13nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM16219(4-(4-chlorophenyl)-4-[4-(1H-pyrazol-4-yl)phenyl]pi...)
Affinity DataIC50:  18nMpH: 7.2 T: 22°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239888(CHEMBL4094292 | US10287286, Example 103)
Affinity DataIC50:  25nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM16218(2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phenyl]et...)
Affinity DataIC50:  31nMpH: 7.2 T: 22°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239915(CHEMBL4067559 | US10287286, Example 6)
Affinity DataIC50:  34nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239937(CHEMBL4083851 | US10287286, Example 3)
Affinity DataIC50:  34nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMedPDB3D3D Structure (crystal)

LigandPNGBDBM16220((2R)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phen...)
Affinity DataIC50:  34nMpH: 7.2 T: 22°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239890(CHEMBL4095005 | US10287286, Example 4)
Affinity DataIC50:  39nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239921(CHEMBL4075128 | US10287286, Example 7)
Affinity DataIC50:  50nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239913(CHEMBL4102714 | US10287286, Example 223)
Affinity DataIC50:  52nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239919(CHEMBL4104731 | US10287286, Example 35)
Affinity DataIC50:  57nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239928(CHEMBL4094977 | US10287286, Example 23)
Affinity DataIC50:  67nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239926(CHEMBL4081861)
Affinity DataIC50:  70nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239880(CHEMBL4076493 | US10287286, Example 8)
Affinity DataIC50:  74nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239908(CHEMBL4093533 | US10287286, Example 21)
Affinity DataIC50:  84nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239910(CHEMBL4073446 | US10287286, Example 209)
Affinity DataIC50:  90nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239917(CHEMBL4068120 | US10287286, Example 31)
Affinity DataIC50:  140nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239929(CHEMBL4076409 | US10287286, Example 30)
Affinity DataIC50:  140nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239927(CHEMBL4086321 | US10287286, Example 29)
Affinity DataIC50:  140nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239914(CHEMBL4078461 | US10287286, Example 222)
Affinity DataIC50:  160nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239909(CHEMBL4059941 | US10287286, Example 15)
Affinity DataIC50:  170nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM16217(4-phenyl-4-[4-(1H-pyrazol-4-yl)phenyl]piperidine |...)
Affinity DataIC50:  200nMpH: 7.2 T: 22°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239911(CHEMBL4094084 | US10287286, Example 26)
Affinity DataIC50:  200nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239912(CHEMBL4064841 | US10287286, Example 34)
Affinity DataIC50:  220nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239893(CHEMBL4081340)
Affinity DataIC50:  240nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239907(CHEMBL4065934 | US10287286, Example 14)
Affinity DataIC50:  270nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239902(CHEMBL4082314 | US10287286, Example 37)
Affinity DataIC50:  280nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM16221((2S)-2-(4-chlorophenyl)-2-[4-(1H-pyrazol-4-yl)phen...)
Affinity DataIC50:  280nMpH: 7.2 T: 22°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239887(CHEMBL4089934 | US10287286, Example 147)
Affinity DataIC50:  460nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239886(CHEMBL4063144 | US10287286, Example 18)
Affinity DataIC50:  460nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM16216(2-phenyl-2-[4-(1H-pyrazol-4-yl)phenyl]ethan-1-amin...)
Affinity DataIC50:  510nMpH: 7.2 T: 22°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239898(CHEMBL4070540 | US10287286, Example 2)
Affinity DataIC50:  550nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239875(CHEMBL4073471)
Affinity DataIC50:  570nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239899(CHEMBL4103861 | US10287286, Example 1)
Affinity DataIC50:  670nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239930(CHEMBL4085560 | US10287286, Example 227)
Affinity DataIC50:  770nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239922(CHEMBL4069766 | US10287286, Example 13)
Affinity DataIC50:  830nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239925(CHEMBL4085789 | US10287286, Example 22)
Affinity DataIC50:  1.28E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239934(CHEMBL4105416)
Affinity DataIC50:  1.30E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239906(CHEMBL4103717 | US10287286, Example 27)
Affinity DataIC50:  1.37E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239923(CHEMBL4100329 | US10287286, Example 221)
Affinity DataIC50:  1.80E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239882(CHEMBL4085434 | US10287286, Example 11)
Affinity DataIC50:  1.87E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239892(CHEMBL4070742)
Affinity DataIC50:  2.50E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM16214(3-[4-(1H-pyrazol-4-yl)phenyl]propan-1-amine | pyra...)
Affinity DataIC50:  3.00E+3nMpH: 7.2 T: 22°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239881(CHEMBL4062995 | US10287286, Example 10)
Affinity DataIC50:  3.90E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

LigandPNGBDBM16213(2-[4-(5-methyl-1H-pyrazol-4-yl)phenyl]ethan-1-amin...)
Affinity DataIC50:  5.20E+3nMpH: 7.2 T: 22°CAssay Description:The purified PKB beta enzyme was assayed with a peptide substrate and test compound in the presence of 30 uM ATP/ [gamma-33P]ATP in 96-well plates. I...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239933(CHEMBL4061916)
Affinity DataIC50:  5.60E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239920(CHEMBL4074091 | US10287286, Example 33)
Affinity DataIC50:  6.10E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

TargetProlyl hydroxylase EGLN2(Human)
Takeda California

Curated by ChEMBL
LigandPNGBDBM50239891(CHEMBL4091624)
Affinity DataIC50:  9.60E+3nMAssay Description:Inhibition of full length HIF-PHD1 (unknown origin) expressed in baculovirus infected sf9 cells using DLDLEMLAPYIPMDDDFQL/2-Oxoglutarate as substrate...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed

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