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Found 187 with Last Name = 'easwaran' and Initial = 'v'
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188343(4-(2,6-dichloro-phenyl)-8-[4-(2-diethylamino-ethox...)
Affinity DataIC50:  2nMAssay Description:Inhibition of human recombinant Lck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186557(1-(6-(4-(2-(diethylamino)ethoxy)phenylamino)pyrimi...)
Affinity DataIC50:  3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186560(1-(6-(4-(2-(diethylamino)ethoxy)phenylamino)pyrimi...)
Affinity DataIC50:  3nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProto-oncogene tyrosine-protein kinase Src(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188343(4-(2,6-dichloro-phenyl)-8-[4-(2-diethylamino-ethox...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Src in presence of 10 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188342(4-(2,6-dichloro-phenyl)-8-(4-morpholin-4-yl-phenyl...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Lck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195334(3-(2-(1H-benzo[d]imidazol-1-yl)-6-(2-(diethylamino...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Lck by ProFlour assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195345(3-(2-(1H-benzo[d]imidazol-1-yl)-6-(4-methylpiperaz...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Lck by ProFlour assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195351(1-(3-(2,5-dimethylbenzyl)-5-(3-cyclohexylpropyl)ph...)
Affinity DataIC50:  3nMAssay Description:Inhibition of human recombinant Lck by ProFlour assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186566(3-(5-((5-tert-butylisoxazol-3-yl)carbamoyl)-2-meth...)
Affinity DataIC50:  4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186535(3-(5-hydroxy-2-methylphenyl)-1-methyl-1-(6-(4-morp...)
Affinity DataIC50:  4nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193999(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((S)-1-phenyle...)
Affinity DataIC50:  4nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195340(3-(4-(benzo[d]isoxazol-3-yl)pyrimidin-2-ylamino)-4...)
Affinity DataIC50:  4.20nMAssay Description:Inhibition of human recombinant Lck by ProFlour assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186556(3-(2,6-dichlorophenyl)-1-methyl-1-(6-(4-(4-methylp...)
Affinity DataIC50:  6nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201514(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-methoxy-7-meth...)
Affinity DataIC50:  6nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195354(CHEMBL220924 | N1-(4-(benzo[d]isoxazol-3-yl)pyrimi...)
Affinity DataIC50:  6.80nMAssay Description:Inhibition of human recombinant Lck by ProFlour assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194011(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N4,N4-dimethyl-N...)
Affinity DataIC50:  7nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193989(CHEMBL221976 | N-((S)-1-(4-fluorophenyl)ethyl)-2-(...)
Affinity DataIC50:  8nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186554(3-(2-chloro-6-methylphenyl)-1-methyl-1-(6-(4-(4-me...)
Affinity DataIC50:  9nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188348(4-(2-chloro-5-hydroxy-phenyl)-8-(4-dimethylamino-p...)
Affinity DataIC50:  10nMAssay Description:Inhibition of human recombinant Lck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201503((2-(3H-imidazo[4,5-c]pyridin-3-yl)-7-methyl-4-((S)...)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  11nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194009(6-(3,4-dimethoxyphenyl)-2-(3H-imidazo[4,5-c]pyridi...)
Affinity DataIC50:  12nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  13nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193995(3-((3R,4R)-4-methyl-3-(methyl(7H-pyrrolo[2,3-d]pyr...)
Affinity DataIC50:  13nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193990(6-(furan-3-yl)-2-(3H-imidazo[4,5-c]pyridin-3-yl)-N...)
Affinity DataIC50:  16nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195338(3-(2-(1H-benzo[d]imidazol-1-yl)-6-(2-morpholinoeth...)
Affinity DataIC50:  17nMAssay Description:Inhibition of human recombinant Lck by ProFlour assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194015(3-(4-(2-chlorophenoxy)-6-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  17nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201514(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-methoxy-7-meth...)
Affinity DataIC50:  18nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193994(4-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
Affinity DataIC50:  18nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194011(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N4,N4-dimethyl-N...)
Affinity DataIC50:  19nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193991(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-(4-methylpiper...)
Affinity DataIC50:  19nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201504(CHEMBL233555 | N-(2-(dimethylamino)ethyl)-2-(3H-im...)
Affinity DataIC50:  19nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194010(6-(4-(dimethylamino)phenyl)-2-(3H-imidazo[4,5-c]py...)
Affinity DataIC50:  20nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188357(4-(2,6-dichloro-phenyl)-8-[4-(2-dimethylamino-ethy...)
Affinity DataIC50:  21nMAssay Description:Inhibition of human recombinant Lck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201512((2-(3H-imidazo[4,5-c]pyridin-3-yl)-7-methyl-4-((S)...)
Affinity DataIC50:  21nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193999(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-((S)-1-phenyle...)
Affinity DataIC50:  21nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201503((2-(3H-imidazo[4,5-c]pyridin-3-yl)-7-methyl-4-((S)...)
Affinity DataIC50:  22nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50195329(3-(2-(1H-benzo[d]imidazol-1-yl)pyrimidin-4-ylamino...)
Affinity DataIC50:  24nMAssay Description:Inhibition of human recombinant Lck by ProFlour assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201516(2-(3H-imidazo[4,5-c]pyridin-3-yl)-N-(2-methoxyethy...)
Affinity DataIC50:  25nMAssay Description:Inhibition of JAK2 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50188352(4-(2,6-dichloro-phenyl)-8-(4-dimethylamino-phenyla...)
Affinity DataIC50:  26nMAssay Description:Inhibition of human recombinant Lck in presence of 10 mM ATPMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194015(3-(4-(2-chlorophenoxy)-6-(4-methylpiperazin-1-yl)p...)
Affinity DataIC50:  27nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186537(3-(2-chloro-6-methylphenyl)-1-(6-(4-(2-(diethylami...)
Affinity DataIC50:  28nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194005(CHEMBL221378 | N-((S)-1-(4-fluorophenyl)ethyl)-6-(...)
Affinity DataIC50:  28nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK2(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194008(3-(4-(furan-3-yl)-6-((S)-1-phenylethylamino)pyrimi...)
Affinity DataIC50:  29nMAssay Description:Inhibition of JAK2More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50194008(3-(4-(furan-3-yl)-6-((S)-1-phenylethylamino)pyrimi...)
Affinity DataIC50:  31nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase Lck(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50186558(1-(6-(4-(2-(diethylamino)ethoxy)phenylamino)pyrimi...)
Affinity DataIC50:  32nMAssay Description:Inhibition of LckMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50201504(CHEMBL233555 | N-(2-(dimethylamino)ethyl)-2-(3H-im...)
Affinity DataIC50:  34nMAssay Description:Inhibition of JAK3 by kinase-Glo luminescent assayMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50132420(3-((1H-pyrrol-2-yl)methylene)-5-(pyridin-3-yl)indo...)
Affinity DataIC50:  38nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetTyrosine-protein kinase JAK3(Homo sapiens (Human))
Procter and Gamble Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50193994(4-(2-(3H-imidazo[4,5-c]pyridin-3-yl)-6-((S)-1-phen...)
Affinity DataIC50:  42nMAssay Description:Inhibition of JAK3More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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