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TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50029464(5-(2-Carboxy-ethyl)-6-[3-(5-ethyl-4'-fluoro-2-hydr...)
Affinity DataKi:  0.470nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50291823(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  0.5nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50291822(19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzyl)-...)
Affinity DataKi:  0.700nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50218796(CHEMBL557978 | OXYMORPHINDOLE CHLORIDE | oxymorphi...)
Affinity DataKi:  0.800nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50291821(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  0.990nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50291821(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  0.990nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50291824(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  1nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetVasopressin V2 receptor(Human)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020673(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  1nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037391(5-{2-(2-Carboxy-ethyl)-3-[6-(4-oxo-8-propyl-chroma...)
Affinity DataKi:  1nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288109(CHEMBL82123 | {2-Benzyl-7-[methyl-(2-piperidin-4-y...)
Affinity DataKi:  1nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetVasopressin V2 receptor(Human)
Smith Kline & French Laboratories

Curated by ChEMBL
LigandPNGBDBM50020667(1-[19-Benzyl-13-carbamoylmethyl-22-(4-ethoxy-benzy...)
Affinity DataKi:  1.10nMAssay Description:Binding affinity of compound towards Vasopressin receptor by binding [3H]-LVP to dog renal medullary preparation.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037390(3-{(S)-2-(2-Carboxy-ethyl)-7-[3-(2-cyclopropylmeth...)
Affinity DataKi:  1.30nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288120(CHEMBL313768 | {2-Cyclohexyl-7-[methyl-(2-piperidi...)
Affinity DataKi:  1.30nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288118(CHEMBL312122 | {2-Methyl-7-[methyl-(2-piperidin-4-...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288119(CHEMBL84073 | {2-Butyl-7-[methyl-(2-piperidin-4-yl...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50074035(CHEMBL82980 | {7-[(4-Carbamimidoyl-phenyl)-methyl-...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50074035(CHEMBL82980 | {7-[(4-Carbamimidoyl-phenyl)-methyl-...)
Affinity DataKi:  1.5nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288115(CHEMBL82746 | {2-(3-Methyl-butyl)-7-[methyl-(2-pip...)
Affinity DataKi:  1.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50054827(CHEMBL85094 | SB-208651 | {8-[(4-Carbamimidoyl-phe...)
Affinity DataKi:  1.60nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50054827(CHEMBL85094 | SB-208651 | {8-[(4-Carbamimidoyl-phe...)
Affinity DataKi:  1.60nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288117(CHEMBL83756 | {2-[2-(4-Fluoro-phenyl)-ethyl]-7-[me...)
Affinity DataKi:  1.70nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50039029((+)-4-((alpha R)-((2S,5R)-4-allyl-2,5-dimethylpipe...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061064((4aR,8aS)-6-Cyclopropylmethyl-8a-(3-hydroxy-phenyl...)
Affinity DataKi:  1.70nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50074030(CHEMBL356020 | {8-[Methyl-(2-piperidin-4-yl-ethyl)...)
Affinity DataKi:  1.90nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50001609(8-Benzyloxy-4-[(methyl-phenethyl-carbamoyl)-methyl...)
Affinity DataKi:  2nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288114(CHEMBL312409 | {2-Isopropyl-7-[methyl-(2-piperidin...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50074044(CHEMBL152156 | [(S)-8-(4-Carbamimidoyl-phenylcarba...)
Affinity DataKi:  2nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288113(CHEMBL311696 | [7-[Methyl-(2-piperidin-4-yl-ethyl)...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288110(CHEMBL84063 | {2-(3,3-Dimethyl-butyl)-7-[methyl-(2...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288108(CHEMBL82727 | {2-(2-Cyclohexyl-ethyl)-7-[methyl-(2...)
Affinity DataKi:  2nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50074029(CHEMBL153162 | [8-(4-Carbamimidoyl-benzoylamino)-3...)
Affinity DataKi:  2nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061063((4aR,8aS)-8a-(3-Hydroxy-phenyl)-3,6-dimethyl-4,4a,...)
Affinity DataKi:  2.10nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288121(CHEMBL310875 | {7-[Methyl-(2-piperidin-4-yl-ethyl)...)
Affinity DataKi:  2.5nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036089(CHEMBL18288 | [8-(4-Carbamimidoyl-phenylcarbamoyl)...)
Affinity DataKi:  2.80nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50036089(CHEMBL18288 | [8-(4-Carbamimidoyl-phenylcarbamoyl)...)
Affinity DataKi:  2.80nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288112(CHEMBL79425 | {7-[Methyl-(2-piperidin-4-yl-ethyl)-...)
Affinity DataKi:  3nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50288111(CHEMBL419838 | {7-[Methyl-(2-piperidin-4-yl-ethyl)...)
Affinity DataKi:  3.20nMAssay Description:In vitro binding affinity against human alpha IIb beta3 integrinMore data for this Ligand-Target Pair
In DepthDetails Article
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50230131(SKF-107260)
Affinity DataKi:  4nMAssay Description:Inhibition of [3H]-107260 binding to purified Fibrinogen receptor of human plateletsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50003319(3-(2-{5-Guanidino-2-[(2-mercapto-benzoyl)-methyl-a...)
Affinity DataKi:  4nMAssay Description:Inhibition of ADP-induced platelet aggregation in canine platelet-rich plasmaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037382(5-{2-(2-Carboxy-ethyl)-3-[(E)-6-(4-methoxy-phenyl)...)
Affinity DataKi:  4nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetIntegrin alpha-IIb/beta-3(Human)
TBA

Curated by ChEMBL
LigandPNGBDBM50074033(CHEMBL151190 | [3-Oxo-4-phenethyl-8-(2-piperidin-4...)
Affinity DataKi:  4.70nMAssay Description:Fibrinogen receptor binding affinity was determined by assaying for inhibition of [3H]-1 binding to purified Fibrinogen Receptor isolated from human...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037376(3-[6-((E)-2-Carboxy-vinyl)-5-(4-phenyl-butoxy)-pyr...)
Affinity DataKi:  4.80nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037389(4-{6-((E)-2-Carboxy-vinyl)-5-[8-(4-methoxy-phenyl)...)
Affinity DataKi:  5.70nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037385(3-{6-((E)-2-Carboxy-vinyl)-5-[6-(4-methoxy-phenyl)...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061062(3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetDelta-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM50061062(3-((4aS,11aR)-2-Ethyl-1,2,3,4,5,6,11,11a-octahydro...)
Affinity DataKi:  7.10nMAssay Description:Binding affinity against Opioid receptor delta 1 using [3H][D-Ala2, D-Leu5]-enkephalin as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037386(3-{6-(2-Carboxy-ethyl)-5-[8-(4-methoxy-phenyl)-oct...)
Affinity DataKi:  8nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetLeukotriene B4 receptor 1(Human)
Smithkline Beecham Pharmaceuticals

Curated by ChEMBL
LigandPNGBDBM50037381(3-{6-((E)-2-Carboxy-vinyl)-5-[4-(4-methoxy-phenyl)...)
Affinity DataKi:  9.20nMAssay Description:Binding affinity at leukotriene B4 receptor on intact human PMNs by displacement of [3H]-LTB4.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetKappa-type opioid receptor(Mouse)
Smithkline Beecham

Curated by ChEMBL
LigandPNGBDBM21864((21R)-22-(cyclopropylmethyl)-14-oxa-11,22-diazahep...)
Affinity DataKi:  9.5nMAssay Description:Binding affinity against Opioid receptor kappa 1 using [3H]-U-69,593 as radioligandMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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