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TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  2.01E+3nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3gamma2 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457445(CHEMBL4212818)
Affinity DataEC50:  860nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  60nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457445(CHEMBL4212818)
Affinity DataEC50:  970nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457445(CHEMBL4212818)
Affinity DataEC50:  2.44E+3nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  130nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  170nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  100nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-1/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  100nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha1beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-2/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457445(CHEMBL4212818)
Affinity DataEC50:  2.29E+3nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-4/beta-3/delta(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  150nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha4beta3delta expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-6/beta-3/gamma-2(Rat)
Johannes Gutenberg University Mainz

Curated by ChEMBL
LigandPNGBDBM50457439(CHEMBL4213357)
Affinity DataEC50:  870nMAssay Description:Modulation of rat eGFP-fused GABA-A receptor alpha6beta3gamma2 expressed in HEK293 cells in presence of GABA by patch-clamp assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/16/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476613(CHEMBL233309)
Affinity DataEC50:  25nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476614(CHEMBL392421)
Affinity DataEC50:  9.80nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476617(CHEMBL391350)
Affinity DataEC50:  13nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476611(CHEMBL233729)
Affinity DataEC50:  11nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476620(CHEMBL231872)
Affinity DataEC50:  46nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476619(CHEMBL394406)
Affinity DataEC50:  52nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476622(CHEMBL233517)
Affinity DataEC50:  155nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476624(CHEMBL233516)
Affinity DataEC50:  16nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476626(CHEMBL395221)
Affinity DataEC50:  32nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476627(CHEMBL233308)
Affinity DataEC50:  3.5nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476625(CHEMBL233740)
Affinity DataEC50:  339nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476621(CHEMBL394408)
Affinity DataEC50:  46nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476616(CHEMBL233311)
Affinity DataEC50:  120nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476628(CHEMBL392422)
Affinity DataEC50:  17nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476615(CHEMBL233310)
Affinity DataEC50:  65nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM9019(CHEMBL45 | N-[2-(5-methoxy-1H-indol-3-yl)ethyl]ace...)
Affinity DataEC50:  0.0794nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
TargetMelatonin receptor type 1C(African clawed frog)
University College London

Curated by ChEMBL
LigandPNGBDBM50476612(CHEMBL233728)
Affinity DataEC50:  3.30nMAssay Description:Effect on pigment aggregation in Xenopus laevis melanophoresMore data for this Ligand-Target Pair
In Depth
Date in BDB:
8/24/2020
Entry Details Article
PubMed
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  1.51E+3nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498762(CHEMBL3622601)
Affinity DataEC50: <1.00E+6nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells at 1 mM by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  724nMAssay Description:Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  720nMAssay Description:Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498756(CHEMBL3622596)
Affinity DataEC50:  1.00E+4nMAssay Description:Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498756(CHEMBL3622596)
Affinity DataEC50:  9.77E+3nMAssay Description:Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM82070(CAS_29790-52-1 | NICOTINE-L (BASE) | Nicotine-D sa...)
Affinity DataEC50:  1.50E+3nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498767(CHEMBL3622597)
Affinity DataEC50:  1.00E+5nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498760(CHEMBL3622603)
Affinity DataEC50:  1.00E+5nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498767(CHEMBL3622597)
Affinity DataEC50:  1.00E+5nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498762(CHEMBL3622601)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells at 1 mM by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498766(CHEMBL3622598)
Affinity DataEC50: <1.00E+6nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells at 1 mM by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50275263(3-(dimethylamino) butyl pyrrolidine-1-carboxylate ...)
Affinity DataEC50:  7.10E+3nMAssay Description:Agonist activity at mouse neuronal acetylcholine receptor subunit alpha4beta2 expressed in HEK293T cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498766(CHEMBL3622598)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells at 1 mM by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498765(CHEMBL3622599)
Affinity DataEC50: <1.00E+6nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells at 1 mM by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498756(CHEMBL3622596)
Affinity DataEC50:  3.24E+4nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498760(CHEMBL3622603)
Affinity DataEC50:  1.00E+5nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498756(CHEMBL3622596)
Affinity DataEC50:  3.20E+4nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
LigandPNGBDBM50498765(CHEMBL3622599)
Affinity DataEC50: >1.00E+6nMAssay Description:Agonist activity at rat neuronal acetylcholine receptor subunit alpha3beta4 expressed in HEK293 cells at 1 mM by FMP assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/3/2020
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50026410(CHEBI:16974 | Imidazole acetic acid)
Affinity DataEC50:  1.74E+3nMAssay Description:Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
TargetGamma-aminobutyric acid receptor subunit alpha-5/beta-2/gamma-2(Human)
University of Copenhagen

Curated by ChEMBL
LigandPNGBDBM50525185(CHEMBL4464494)
Affinity DataEC50:  1.10E+4nMAssay Description:Agonist activity at recombinant human GABA-A alpha5beta2gamma2S receptor transiently expressed in human tsA201 cells incubated for 30 mins and measur...More data for this Ligand-Target Pair
In Depth
Date in BDB:
2/24/2021
Entry Details Article
PubMed
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