Report error Found 311 with Last Name = 'fracasso' and Initial = 'c'
Affinity DataEC50: 32nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 9.5nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 1.60nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 4.20nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 54nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 12nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 3nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 15nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 1nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 14nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 6.60nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 3.80nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 2.70nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 2.40nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 4.20nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 1.70nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 7.20nMAssay Description:Effective concentration against 5-Hydroxytryptamine 3 receptor by measuring [14C]guanidinium uptake on NG108-15 cells.More data for this Ligand-Target Pair
Affinity DataEC50: 4.50E+6nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 490nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 630nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
Affinity DataEC50: 310nMAssay Description:Agonist activity at 5HT7 receptor assessed as relaxation of substance P-induced Dunkin-Hartley guinea pig ileum contractionMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Guinea pig)
European Research Centre For Drug Discovery and Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery and Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 340nMAssay Description:Intrinsic activity at 5HT3 receptor in voltage-stimulated guinea pig left atrium assessed as positive inotropic potency relative to serotoninMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Guinea pig)
European Research Centre For Drug Discovery and Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery and Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataEC50: 160nMAssay Description:Agonist activity at 5HT3 receptor in voltage-stimulated guinea pig left atrium assessed as positive inotropic potencyMore data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Guinea pig)
European Research Centre For Drug Discovery and Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery and Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKd: 64.6nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
Target5-hydroxytryptamine receptor 3A(Guinea pig)
European Research Centre For Drug Discovery and Development (Natsyndrugs)
Curated by ChEMBL
European Research Centre For Drug Discovery and Development (Natsyndrugs)
Curated by ChEMBL
Affinity DataKd: 955nMAssay Description:Antagonist activity at 5HT3 receptor in spontaneously beating guinea pig right atrium assessed as inhibition of serotonin-induced maximum response by...More data for this Ligand-Target Pair
Affinity DataIC50: 0.260nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 3 receptor from NG108-15 cells using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.370nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
Affinity DataIC50: 0.440nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
Affinity DataIC50: 0.670nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.790nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 0.810nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.13nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 1.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2.10nMAssay Description:Inhibition of radiolabeled [3H]-Zacopride ligand binding to 5-hydroxytryptamine 3 receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 2.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2.30nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Inhibition of radiolabeled [3H]-8-OH-DPAT ligand binding to 5-hydroxytryptamine 1A receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3.10nMAssay Description:Inhibition of radiolabeled [3H]-Ketanserin ligand binding to 5-hydroxytryptamine 2C receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 3.60nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3.80nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 3.90nMAssay Description:Inhibition of [3H]BRL-43694 binding to 5-hydroxytryptamine 3 receptor of rat cortical homogenate.More data for this Ligand-Target Pair
Affinity DataIC50: 4.60nMAssay Description:Inhibition of radiolabeled [3H]-5-HT ligand binding to 5-hydroxytryptamine 1B receptorMore data for this Ligand-Target Pair
Affinity DataIC50: 5.20nMAssay Description:Binding affinity against 5-hydroxytryptamine 3 (5-HT3) receptor from rat cortical homogenate using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
Affinity DataIC50: 5.40nMAssay Description:The compound was tested for binding affinity against 5-hydroxytryptamine 3 receptor from NG108-15 cells using [3H]zacopride as radioligandMore data for this Ligand-Target Pair
