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TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426967(PF-4693627 | CHEMBL2325079)
Affinity DataIC50: 3nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426956(CHEMBL2325076)
Affinity DataIC50: 8.30nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426958(CHEMBL2325074)
Affinity DataIC50: 15nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426955(CHEMBL2325077)
Affinity DataIC50: 16nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426954(CHEMBL2325078)
Affinity DataIC50: 19nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426963(CHEMBL2325084)
Affinity DataIC50: 25nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426957(CHEMBL2325075)
Affinity DataIC50: 33nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426960(CHEMBL2325072)
Affinity DataIC50: 34nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426964(CHEMBL2325083)
Affinity DataIC50: 39nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426966(CHEMBL2325080)
Affinity DataIC50: 65nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426965(CHEMBL2325082)
Affinity DataIC50: 72nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426956(CHEMBL2325076)
Affinity DataIC50: 74nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426958(CHEMBL2325074)
Affinity DataIC50: 88nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426965(CHEMBL2325082)
Affinity DataIC50: 110nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426967(PF-4693627 | CHEMBL2325079)
Affinity DataIC50: 110nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426961(CHEMBL2325351)
Affinity DataIC50: 130nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataIC50: 150nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426957(CHEMBL2325075)
Affinity DataIC50: 174nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426955(CHEMBL2325077)
Affinity DataIC50: 180nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426954(CHEMBL2325078)
Affinity DataIC50: 250nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069128(CHEMBL3403524)
Affinity DataIC50: 300nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50425318(CHEMBL2315861)
Affinity DataIC50: 300nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426966(CHEMBL2325080)
Affinity DataIC50: 340nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426963(CHEMBL2325084)
Affinity DataIC50: 340nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069104(CHEMBL1449583 | US9182402, 4)
Affinity DataIC50: 350nMAssay Description:Inhibition of hepsin (unknown origin)More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426960(CHEMBL2325072)
Affinity DataIC50: 570nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426964(CHEMBL2325083)
Affinity DataIC50: 600nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069127(CHEMBL3403525)
Affinity DataIC50: 600nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426962(CHEMBL2325085)
Affinity DataIC50: 610nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426959(CHEMBL2325073)
Affinity DataIC50: 706nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069132(CHEMBL550687)
Affinity DataIC50: 820nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069133(CHEMBL1195245)
Affinity DataIC50: 1.10E+3nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426959(CHEMBL2325073)
Affinity DataIC50: 1.40E+3nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50425330(CHEMBL2315870)
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426961(CHEMBL2325351)
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069129(CHEMBL3403523)
Affinity DataIC50: 3.00E+3nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426968(CHEMBL2325086)
Affinity DataIC50: 4.20E+3nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426969(CHEMBL2325081)
Affinity DataIC50: 6.70E+3nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069131(CHEMBL3403522)
Affinity DataIC50: 6.80E+3nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50426962(CHEMBL2325085)
Affinity DataIC50: 7.40E+3nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50425318(CHEMBL2315861)
Affinity DataIC50: 1.10E+4nMAssay Description:Inhibition of mPGES1 mediated PGE2 production in LPS-stimulated human whole blood by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50424712(Camostat Mesilate | Foipan | CAMOSTAT)
Affinity DataIC50: 3.20E+4nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetProstaglandin E synthase(Human)
Pfizer

Curated by ChEMBL
LigandPNGBDBM50425319(CHEMBL2315860)
Affinity DataIC50: 3.30E+4nMAssay Description:Inhibition of human mPGES1 by ELISAMore data for this Ligand-Target Pair
In Depth
Date in BDB:
9/24/2013
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069123(CHEMBL579653)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069124(CHEMBL535214)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069125(CHEMBL3403527)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetHepatocyte growth factor activator(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50069126(CHEMBL3403526)
Affinity DataIC50: 5.00E+4nMAssay Description:Inhibition of recombinant N-terminal His-tagged HGFA (unknown origin) expressed in baculovirus-infected Sf9 cells incubated for 30 mins prior to crom...More data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataKi:  0.0200nMAssay Description:Inhibition of matripase (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetSerine protease hepsin(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM50063698(4-Guanidino-benzoic acid 6-carbamimidoyl-naphthale...)
Affinity DataKi:  0.530nMAssay Description:Inhibition of hepsin (unknown origin) using Boc-QAR-AMC as substrate after 30 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
TargetSuppressor of tumorigenicity 14 protein(Human)
Washington University

Curated by ChEMBL
LigandPNGBDBM23887(4-({4-[(2S)-3-(3-carbamimidoylphenyl)-2-{[2,4,6-tr...)
Affinity DataKi:  4.30nMAssay Description:Inhibition of matripase (unknown origin) using Boc-QAR-AMC as substrate incubated for 30 mins prior to substrate addition by fluorescence assayMore data for this Ligand-Target Pair
In Depth
Date in BDB:
4/14/2016
Entry Details Article
PubMed
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