Compile Data Set for Download or QSAR
Report error Found 290 with Last Name = 'gaboriaud-kolar' and Initial = 'n'
TargetProtein polybromo-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50198438(CHEMBL3904183)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to N-terminal his6-tagged human PB1 bromodomain 5 expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 at 15 uM by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50198451(CHEMBL1491707)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to N-terminal his6-tagged human PB1 bromodomain 5 expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 at 15 uM by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50198448(CHEMBL3966713)
Affinity DataKd:  3.40E+3nMAssay Description:Binding affinity to N-terminal his6-tagged human PB1 bromodomain 5 expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 at 15 uM by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM7459(2-(3,4-dihydroxyphenyl)-5,7-dihydroxy-4H-chromen-4...)
Affinity DataKd:  1.29E+4nMAssay Description:Binding affinity to N-terminal his6-tagged human PB1 bromodomain 5 expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 at 15 uM by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMedPDB3D3D Structure (crystal)
TargetProtein polybromo-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50198440(CHEMBL3945847)
Affinity DataKd:  1.15E+4nMAssay Description:Binding affinity to N-terminal his6-tagged human PB1 bromodomain 5 expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 at 15 uM by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50198447(CHEMBL3899245)
Affinity DataKd:  43nMAssay Description:Binding affinity to N-terminal his6-tagged human PB1 bromodomain 5 expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 at 15 uM by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50198450(CHEMBL3927964)
Affinity DataKd:  5.10E+3nMAssay Description:Binding affinity to N-terminal his6-tagged human PB1 bromodomain 5 expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 at 15 uM by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProtein polybromo-1(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50198449(CHEMBL3936967)
Affinity DataKd:  3.30E+3nMAssay Description:Binding affinity to N-terminal his6-tagged human PB1 bromodomain 5 expressed in Escherichia coli BL21 (DE3)-R3-pRARE2 at 15 uM by ITC methodMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 0.5nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 0.610nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252767(CHEMBL493657 | (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2...)
Affinity DataIC50: 0.830nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 0.870nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 2.20nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 3.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 4.90nMAssay Description:Inhibition of recombinant c-Src (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Pig)
University of Athens

Curated by ChEMBL
LigandPNGBDBM7401(6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...)
Affinity DataIC50: 5nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 7.10nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 7.20nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 9.40nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252767(CHEMBL493657 | (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2...)
Affinity DataIC50: 15nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252767(CHEMBL493657 | (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2...)
Affinity DataIC50: 34nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252767(CHEMBL493657 | (2'Z-3'E)-6-Bromoindirubin-3'-[O-(2...)
Affinity DataIC50: 34.1nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 41.5nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 42nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 67nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Pig)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50426336(CHEMBL2321952)
Affinity DataIC50: 70nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 79nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM7401(6-bromoindirubin-3 -oxime | (3E)-6-bromo-3-[3-(hyd...)
Affinity DataIC50: 83nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Pig)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50426339(CHEMBL2321961)
Affinity DataIC50: 100nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 107nMAssay Description:Inhibition of recombinant ABL1 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50426339(CHEMBL2321961)
Affinity DataIC50: 110nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50426338(CHEMBL2321958)
Affinity DataIC50: 130nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50426337(CHEMBL1233659)
Affinity DataIC50: 130nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252978(CHEMBL493883 | CHEMBL494685 | (2'Z-3'E)-6-Bromoind...)
Affinity DataIC50: 175nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 178nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase ABL1(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252727((2'Z-3'E)-6-Bromoindirubin-3'-(O-{2-[N-methyl,N-(2...)
Affinity DataIC50: 194nMAssay Description:Inhibition of recombinant ABL1 T315I mutant (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetProto-oncogene tyrosine-protein kinase Src(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50259592(CHEMBL4080255)
Affinity DataIC50: 200nMAssay Description:Inhibition of recombinant GST-tagged c-Src (unknown origin) expressed in insect cells using pEY as substrate preincubated with enzyme followed by [33...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetGlycogen synthase kinase-3 beta(Pig)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50426334(CHEMBL2321948)
Affinity DataIC50: 200nMAssay Description:Inhibition of porcine brain GSK3beta using YRRAAVPPSPSLSRHSSPHQSpEDEEE as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50426338(CHEMBL2321958)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCyclin-dependent kinase 5(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50426334(CHEMBL2321948)
Affinity DataIC50: 200nMAssay Description:Inhibition of human recombinant CDK5More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50426337(CHEMBL1233659)
Affinity DataIC50: 210nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50426338(CHEMBL2321958)
Affinity DataIC50: 220nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetTyrosine-protein kinase JAK2(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252729(CHEMBL3216659 | CHEMBL522503 | (2''Z-3''E)-6-Bromo...)
Affinity DataIC50: 224nMAssay Description:Inhibition of recombinant JAK2 (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetCasein kinase I isoform alpha(Pig)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50426312(CHEMBL2321951)
Affinity DataIC50: 300nMAssay Description:Inhibition of porcine brain CK1 using RRKHAAIGpSAYSITA as substrateMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
LigandPNGBDBM50426336(CHEMBL2321952)
Affinity DataIC50: 310nMAssay Description:Inhibition of rat recombinant GST-fused DYRK1A expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation countin...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetAurora kinase A(Human)
Beckman Research Institute

Curated by ChEMBL
LigandPNGBDBM50252730(CHEMBL3215571 | (2'Z-3'E)-6-Bromoindirubin-3'-(O-{...)
Affinity DataIC50: 330nMAssay Description:Inhibition of recombinant Aurora A (unknown origin) after 120 mins in presence of [33P]ATPMore data for this Ligand-Target Pair
In DepthDetails Article
PubMed
TargetDual specificity tyrosine-phosphorylation-regulated kinase 2(Human)
University of Athens

Curated by ChEMBL
LigandPNGBDBM50426336(CHEMBL2321952)
Affinity DataIC50: 350nMAssay Description:Inhibition of human recombinant GST-fused DYRK2 expressed in Escherichia coli using KKISGRLSPIMTEQ as substrate after 30 mins by scintillation counti...More data for this Ligand-Target Pair
In DepthDetails Article
PubMed
Displayed 1 to 50 (of 290 total ) | Next | Last >>
Jump to: